SCHEMBL5373971

SCHEMBL5373971

CN(CCO)c1ccc(N)cc1N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.41
KDM4E B2RXH2 3/20 0.41
CASP1 P29466 6/20 0.38
GAA P10253 4/20 0.37
MAPT P10636 4/20 0.37
MAPK1 P28482 1/20 0.37
KMT2A Q03164 5/20 0.35
MEN1 O00255 3/20 0.33
USP2 O75604 3/20 0.33
CASP7 P55210 3/20 0.33
HSD17B10 Q99714 3/20 0.33
TP53 P04637 2/20 0.33
HTT P42858 2/20 0.33
HPGD P15428 2/20 0.33
HBB P68871 2/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
PRKCI P41743 1/20 0.33
CYP19A1 P11511 1/20 0.33
POLB P06746 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30221431 0.83 HRH3 (0.40) ALDH1A1KDM4ECASP1GAAMAPT
SCHEMBL11751589 0.83 HRH3 (0.40) ALDH1A1KDM4ECASP1GAAMAPT
SCHEMBL6816397 0.82 CYP3A4 (0.41) ALDH1A1KDM4ECASP1GAAMAPT
SCHEMBL30660966 0.82 ALDH1A1 (0.39) ALDH1A1KDM4ECASP1GAAMAPT
SCHEMBL594693 0.82 ALDH1A1 (0.39) ALDH1A1KDM4ECASP1GAAMAPT
SCHEMBL880664 0.82 ALDH1A1 (0.39) ALDH1A1KDM4ECASP1GAAMAPT
SCHEMBL357955 0.82 GAA (0.58) ALDH1A1KDM4EGAAMAPTMAPK1
SCHEMBL8640578 0.81 CASP1 (0.35) ALDH1A1KDM4ECASP1GAAMAPT
SCHEMBL24992424 0.81 ALDH1A1 (0.41) ALDH1A1KDM4ECASP1GAAMAPT
SCHEMBL15586105 0.80 CASP1 (0.36) ALDH1A1KDM4ECASP1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7163784-B2 Silver halide emulsion, and silver halide color photographic material using the same KONICA MINOLTA PHOTO IMAGING, INC. (JP) 2007-01-16 US disclosed
EP-1630598-A2 Silver halide emulsion, and silver halide color photographic material using the same Konica Minolta Photo Imaging, Inc. (JP) 2006-03-01 EP disclosed
US-20060040220-A1 Silver halide emulsion, and silver halide color photographic material using the same KONICA MINOLTA PHOTO IMAGING, INC. 2006-02-23 US disclosed