Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | GRN | P28799 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30479179 | 0.82 | MALT1 (0.42) | MALT1BAZ2BALDH1A1NQO2NPC1 | |
| SCHEMBL8574212 | 0.81 | BAZ2B (0.58) | MALT1BAZ2BALDH1A1NPC1RAB9A | |
| SCHEMBL20528966 | 0.79 | MALT1 (0.40) | MALT1BAZ2BALDH1A1NQO2NPC1 | |
| SCHEMBL30793123 | 0.79 | MALT1 (0.40) | MALT1BAZ2BALDH1A1NQO2NPC1 | |
| SCHEMBL2386056 | 0.79 | KDM4E (0.51) | MALT1BAZ2BALDH1A1NQO2NPC1 | |
| SCHEMBL31460285 | 0.79 | MALT1 (0.40) | MALT1BAZ2BALDH1A1NQO2NPC1 | |
| SCHEMBL31739403 | 0.79 | MALT1 (0.38) | MALT1BAZ2BALDH1A1NQO2NPC1 | |
| SCHEMBL17522579 | 0.78 | BAZ2B (0.40) | BAZ2BALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL2152111 | 0.78 | HCAR2 (0.41) | BAZ2BALDH1A1KDM4EGRNSORT1 | |
| SCHEMBL4751927 | 0.76 | PLA2G10 (0.49) | BAZ2BALDH1A1KDM4EL3MBTL1PLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102659683-B | Process for production of 5-alkoxy-4-hydroxymethylpyrazole compound | IHARA CHEMICAL IND CO | 2014-11-12 | — | — | CN | disclosed |
| CN-1938278-B | Process for producing 5-hydroxy-4-thiomethylpyrazole compound | IHARA CHEMICAL IND CO | 2012-12-12 | — | — | CN | disclosed |
| CN-102659683-A | Process for production of 5-alkoxy-4-hydroxymethylpyrazole compound | IHARA CHEMICAL IND CO | 2012-09-12 | — | — | CN | disclosed |
| CN-101384556-B | Process for producing 5-alkoxy-4-hydroxymethylpyrazole compound | IHARA CHEMICAL IND CO | 2012-06-20 | — | — | CN | disclosed |
| EP-1990336-B1 | PROCESS FOR PRODUCTION OF 5-ALKOXY-4-HYDROXYMETHYLPYRAZOLE COMPOUND | IHARA CHEMICAL IND CO (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-7812175-B2 | Process for production of 5-alkoxy-4-hydroxymethylpyrazole compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-10-12 | — | — | US | disclosed |
| CN-101384556-A | Process for producing 5-alkoxy-4-hydroxymethylpyrazole compound | IHARA CHEMICAL IND CO (JP) | 2009-03-11 | — | — | CN | disclosed |
| US-7488831-B2 | Process for producing 5-hydroxy-4-thiomethylpyrazole compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-02-10 | — | — | US | disclosed |
| US-20090036688-A1 | Process for Production of 5-Alkoxy-4-Hydroxymethylpyrazole Compound | IHARA CHEMICAL INDUSTRY CO., LTD (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1990336-A1 | PROCESS FOR PRODUCTION OF 5-ALKOXY-4-HYDROXYMETHYLPYRAZOLE COMPOUND | Ihara Chemical Industry Co., Ltd. (JP) | 2008-11-12 | — | — | EP | disclosed |
| US-20070185334-A1 | Process for producing 5-hydroxy-4-thiomethylpyrazole compound | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-08-09 | — | — | US | disclosed |
| EP-1767528-A1 | PROCESS FOR PRODUCING 5-HYDROXY-4-THIOMETHYLPYRAZOLE COMPOUND | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2007-03-28 | — | — | EP | disclosed |
| CN-1938278-A | Process for producing 5-hydroxy-4-thiomethylpyrazole compound | IHARA CHEMICAL IND CO (JP) | 2007-03-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036688-A1 | Process for Production of 5-Alkoxy-4-Hydroxymethylpyrazole Compound | CYP4F3, ADH5, CYP3A4 | MALT1 3846/4885BAZ2B 2378/4885ALDH1A1 175/4885 |
| US-20070185334-A1 | Process for producing 5-hydroxy-4-thiomethylpyrazole compound | CYP3A5, CYP4F11, GTF3C5 | MALT1 3470/4885BAZ2B 3317/4885ALDH1A1 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.