SCHEMBL5374528

SCHEMBL5374528

CO[SiH](OC)OC(C)(C)CC(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9161729 0.80
SCHEMBL11660569 0.73
Isopropyl Alcohol SCHEMBL8918581 0.73 ALDH1A1 (0.39)
SCHEMBL9157191 0.70
Propane SCHEMBL8915713 0.70 ALDH1A1 (0.46)
SCHEMBL297420 0.68 MMP8 (0.30)
SCHEMBL3717631 0.68 MMP8 (0.30)
SCHEMBL24683753 0.65
SCHEMBL1194197 0.65
SCHEMBL4941677 0.65 MAPK1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0419249-B1 Silane-modified supported polyolefin catalyst to produce a broadened molecular weight distribution product AMOCO CORP (US) 1995-02-22 EP claimed
US-4990478-A Ccordination catalysts AMOCO CORPORATION (US) 1991-02-05 US claimed
US-11427660-B2 Organosilicon compounds as electron donors for olefin polymerization catalysts and methods of making and using same FORMOSA PLASTICS CORPORATION, USA (US) 2022-08-30 US disclosed
EP-2969201-B1 NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS FORMOSA PLASTICS CORP USA (US) 2022-05-04 EP disclosed
US-10954324-B2 Catalyst component for high activity and high stereoselectivity in olefin polymerization FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2021-03-23 US disclosed
US-20180066084-A1 Catalyst Component for High Activity and high Stereoselectivity in Olefin Polymerization FORMOSA PLASTICS CORPORATION, U.S.A. 2018-03-08 US disclosed
US-20180051105-A1 Organosilicon Compounds as Electron Donors for Olefin Polymerization Catalysts and Methods of Making and Using Same FORMOSA PLASTICS CORPORATION, USA 2018-02-22 US disclosed
US-9815918-B2 Catalyst component for high activity and high stereoselectivity in olefin polymerization FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2017-11-14 US disclosed
US-9790291-B2 Non-phthalate compounds as electron donors for polyolefin catalysts FORMOSA PLASTICS CORPORATION, USA (US) 2017-10-17 US disclosed
EP-2969201-A2 NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS Formosa Plastics Corporation, U.S.A. (US) 2016-01-20 EP disclosed
WO-2014160012-A2 NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS FORMOSA PLASTICS CORPORATION, USA (US) 2014-10-02 WO disclosed
US-20040198931-A1 Magnesium compound, olefin polymerization catalyst, and method for producing olefin polymer IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-10-07 US disclosed
US-6777365-B2 BULK DENSITY; NARROW PARTICLE SIZE DISTRIBUTION IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-08-17 US disclosed
CN-1117773-C Solid catalyst component for alpha-olefin polymerization, catalyst for alpha-olefin polymerization, and process for producing alpha-olefin polymer SUMITOMO CHEMICAL CO (JP) 2003-08-13 CN disclosed
US-20010012908-A1 Magnesium compound, olefin polymerization catalyst, and method for producing olefin polymer IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-08-09 US disclosed
EP-1108730-A1 Magnesium compound, olefin polymerization catalyst and method for producing olefin polymer IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-06-20 EP disclosed
CN-1174850-A Solid catalyst component for alpha-olefin polymerization, catalyst for alpha-olefin polymerization, and process for producing alpha-olefin polymer SUMITOMO CHEMICAL CO (JP) 1998-03-04 CN disclosed
EP-0419249-B1 Silane-modified supported polyolefin catalyst to produce a broadened molecular weight distribution product AMOCO CORP (US) 1995-02-22 EP disclosed
EP-0419249-A2 Silane-modified supported polyolefin catalyst to produce a broadened molecular weight distribution product AMOCO CORPORATION (US) 1991-03-27 EP disclosed
US-4990478-A Ccordination catalysts AMOCO CORPORATION (US) 1991-02-05 US disclosed