Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 9/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.62 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.60 |
| ▸ | PPARA | Q07869 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8955671 | 0.94 | LTA4H (0.67) | LTA4HALDH1A1RECQLPLA2G2AKCNA3 | |
| SCHEMBL24398832 | 0.92 | LTA4H (0.65) | LTA4HALDH1A1RECQLPLA2G2AKCNA3 | |
| SCHEMBL2075482 | 0.92 | LTA4H (0.65) | LTA4HALDH1A1RECQLPLA2G2AKCNA3 | |
| SCHEMBL50192 | 0.91 | ALDH1A1 (0.77) | LTA4HALDH1A1RECQLKCNA3HDAC1 | |
| SCHEMBL2296317 | 0.89 | ALDH1A1 (0.83) | LTA4HALDH1A1RECQLPLA2G2AKCNA3 | |
| Phenoxyethanol SCHEMBL8201120 | 0.87 | ALDH1A1 (0.86) | LTA4HALDH1A1RECQLKCNA3HDAC1 | |
| SCHEMBL11705181 | 0.86 | KDM4E (0.59) | LTA4HALDH1A1RECQLKCNA3TSHR | |
| SCHEMBL95951 | 0.85 | KCNA3 (0.76) | LTA4HALDH1A1RECQLKCNA3HDAC1 | |
| Diphenylether SCHEMBL1373717 | 0.84 | LTA4H (0.63) | LTA4HALDH1A1RECQLPLA2G2AKCNA3 | |
| SCHEMBL8671305 | 0.84 | LTA4H (0.75) | LTA4HALDH1A1RECQLPLA2G2AKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | ELI LILLY AND COMPANY | 2005-01-27 | — | — | US | disclosed |
| EP-1392637-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100813-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-12-19 | — | — | WO | disclosed |
| US-5280036-A | Containing 4h-1,24-triazole ring | BASF AKTIENGESELLSCHAFT (DE) | 1994-01-18 | — | — | US | disclosed |
| US-5214064-A | Insecticides, nematocides, miticides | BASF AKTIENGESELLSCHAFT (DE) | 1993-05-25 | — | — | US | disclosed |
| EP-0289919-B1 | N-SUBSTITUTED AZOLES | BASF Aktiengesellschaft (DE) | 1993-03-17 | — | — | EP | disclosed |
| US-5187182-A | Insecticides, nematocides | BASF AKTIENGESELLSCHAFT (DE) | 1993-02-16 | — | — | US | disclosed |
| US-5185359-A | N-phenoxphenyloxymethyl substituted azoles and method for controlling pests therewith | BASF AKTIENGESELLSCHAFT (DE) | 1993-02-09 | — | — | US | disclosed |
| US-5116860-A | N-SUBSTITUTED AZOLES FOR COMBATING INSECTS, ARACHNIDS AND NEMATODES | BASF AKTIENGESELLSCHAFT (DE) | 1992-05-26 | — | — | US | disclosed |
| US-4943585-A | N-substituted azoles and insecticide, arachnicide, and nematocide compositions thereof | BASF AKTIENGESELLSCHAFT (DE) | 1990-07-24 | — | — | US | disclosed |
| EP-0289919-A2 | N-Substituted azoles | BASF Aktiengesellschaft (DE) | 1988-11-09 | — | — | EP | disclosed |
| US-4048327-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | NCOA4, PPARG, PPARA | LTA4H 2072/4885ALDH1A1 2292/4885RECQL 2823/4885 |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | PPARG, NCOA4, PPARA | LTA4H 2124/4885ALDH1A1 2029/4885RECQL 2751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.