Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.41 |
| ▸ | PGK2 | P07205 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11888529 | 0.85 | ENPP2 (0.45) | ENPP2PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL3279344 | 0.85 | HDAC4 (0.47) | ENPP2PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL26672647 | 0.84 | TDP1 (0.45) | MEN1KMT2AUGT2B7LMNAPGK1 | |
| SCHEMBL28037741 | 0.84 | TDP1 (0.45) | MEN1KMT2AUGT2B7LMNAPGK1 | |
| SCHEMBL3919972 | 0.83 | PTGS2 (0.46) | MEN1KMT2AUGT2B7LMNAPGK1 | |
| SCHEMBL19759679 | 0.83 | ENPP2 (0.44) | ENPP2PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL3919970 | 0.83 | PTGS2 (0.46) | MEN1KMT2AUGT2B7LMNAPGK1 | |
| SCHEMBL10606510 | 0.83 | ENPP2 (0.47) | ENPP2PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL23343765 | 0.82 | ENPP2 (0.42) | ENPP2PRSS1PRSS2PRSS3TSHR | |
| SCHEMBL16952892 | 0.82 | ENPP2 (0.42) | ENPP2PRSS1PRSS2PRSS3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9987381-B2 | Radioligands for imaging the LPA-1 receptor | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-06-05 | — | — | US | disclosed |
| US-20160256577-A1 | RADIOLIGANDS FOR IMAGING THE LPA-1 RECEPTOR | BRISTOL MYERS SQUIBB CO (US) | 2016-09-08 | — | — | US | disclosed |
| EP-3062827-A1 | RADIOLIGANDS FOR IMAGING THE LPA-1 RECEPTOR | Bristol-Myers Squibb Company (US) | 2016-09-07 | — | — | EP | disclosed |
| WO-2015066456-A1 | RADIOLIGANDS FOR IMAGING THE LPA-1 RECEPTOR | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-05-07 | — | — | WO | disclosed |
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | ELI LILLY AND COMPANY | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160256577-A1 | RADIOLIGANDS FOR IMAGING THE LPA-1 RECEPTOR | LPAR1, LPAR3, LPAR2 | MEN1 1354/4885KMT2A 3297/4885UGT2B7 2648/4885 |
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | NCOA4, PPARG, PPARA | MEN1 4860/4885KMT2A 2887/4885UGT2B7 1113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.