Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1767594 | 0.79 | LMNA (0.44) | ALDH1A1CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL1767595 | 0.79 | LMNA (0.44) | ALDH1A1CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL9404760 | 0.78 | CA1 (0.45) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL4650108 | 0.75 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL21558734 | 0.70 | GSK3B (0.38) | ALDH1A1TYRALOX5MAPTCYP2C9 | |
| SCHEMBL239301 | 0.70 | MAPT (0.47) | ALDH1A1ITGB1ITGA5MAPTCYP2C9 | |
| SCHEMBL239300 | 0.70 | MAPT (0.47) | ALDH1A1ITGB1ITGA5MAPTCYP2C9 | |
| Water SCHEMBL9435219 | 0.68 | MAPT (0.45) | ALDH1A1ITGB1ITGA5MAPTCYP2C9 | |
| SCHEMBL9706327 | 0.68 | ALDH1A1 (0.54) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL11441110 | 0.68 | ALDH1A1 (0.54) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7271253-B1 | Safe process for the preparation of balsalazide | APOTEX PHARMACHEM INC. (CA) | 2007-09-18 | — | — | US | claimed |