Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.83 |
| ▸ | LMNA | P02545 | 6/20 | 0.83 |
| ▸ | THRB | P10828 | 2/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.83 |
| ▸ | MEN1 | O00255 | 1/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.83 |
| ▸ | PLG | P00747 | 1/20 | 0.83 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.83 |
| ▸ | RECQL | P46063 | 1/20 | 0.83 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.83 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.78 |
| ▸ | BLM | P54132 | 3/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.74 |
| ▸ | TSHR | P16473 | 3/20 | 0.72 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.72 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.72 |
| ▸ | GABRP | O00591 | 1/20 | 0.72 |
| ▸ | GABRD | O14764 | 1/20 | 0.72 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL2450010 | 1.00 | LMNA (0.83) | LMNATHRBKMT2AMEN1ALDH1A1 | |
| Succinic Acid SCHEMBL8577076 | 1.00 | LMNA (0.83) | LMNATHRBKMT2AMEN1ALDH1A1 | |
| Succinic Acid SCHEMBL8434204 | 1.00 | LMNA (0.83) | LMNATHRBKMT2AMEN1ALDH1A1 | |
| Adipic Acid SCHEMBL931429 | 0.91 | LMNA (1.00) | LMNATHRBKMT2AMEN1ALDH1A1 | |
| Aminocaproic Acid SCHEMBL21141584 | 0.91 | LMNA (1.00) | LMNATHRBKMT2AMEN1ALDH1A1 | |
| Glutarate SCHEMBL2447120 | 0.91 | LMNA (0.89) | LMNATHRBKMT2AMEN1ALDH1A1 | |
| 12-Aminododecanoic Acid SCHEMBL20767098 | 0.91 | LMNA (1.00) | LMNATHRBKMT2AMEN1ALDH1A1 | |
| Pimelic Acid SCHEMBL21465298 | 0.91 | LMNA (1.00) | LMNATHRBKMT2AMEN1ALDH1A1 | |
| 12-Aminododecanoic Acid SCHEMBL8973700 | 0.91 | LMNA (1.00) | LMNATHRBKMT2AMEN1ALDH1A1 | |
| Adipic Acid SCHEMBL11332689 | 0.91 | LMNA (1.00) | LMNATHRBKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112852692-B | Recombinant escherichia coli for producing 1, 5-pentanediamine-succinate and construction method and application thereof | 中国科学院天津工业生物技术研究所 | 2022-05-31 | — | — | CN | claimed |
| CN-109180494-B | Pentanediamine succinate and crystal thereof | 南京工业大学 | 2021-07-16 | — | — | CN | claimed |
| CN-112852692-A | Recombinant escherichia coli for producing 1, 5-pentanediamine-succinate and construction method and application thereof | 中国科学院天津工业生物技术研究所 | 2021-05-28 | — | — | CN | claimed |
| WO-2026100897-A1 | LYSINE DECARBOXYLASE DERIVED FROM PANTOEA ALHAGI AND METHOD FOR PRODUCING CADAVERINE USING MICROORGANISM COMPRISING SAME | 씨제이제일제당 (주) | 2026-05-15 | — | — | WO | disclosed |
| CN-121752727-A | Process for preparing cadaverine dicarboxylic acid salts | CJ第一制糖株式会社 | 2026-03-27 | — | — | CN | disclosed |
| CN-119875980-A | Recombinant escherichia coli NT 1003-delta ldhA-YPK-cadA and application thereof in co-production of pentanediamine and succinate | 南京工业大学 | 2025-04-25 | — | — | CN | disclosed |
| CN-118580152-A | Method for separating and extracting biobased nylon-54 precursor from co-fermentation liquid | 南京工业大学 | 2024-09-03 | — | — | CN | disclosed |
| CN-112852692-B | Recombinant escherichia coli for producing 1, 5-pentanediamine-succinate and construction method and application thereof | 中国科学院天津工业生物技术研究所 | 2022-05-31 | — | — | CN | disclosed |
| CN-112852692-B | Recombinant escherichia coli for producing 1, 5-pentanediamine-succinate and construction method and application thereof | 中国科学院天津工业生物技术研究所 | 2022-05-31 | — | — | CN | disclosed |
| CN-112852692-B | Recombinant escherichia coli for producing 1, 5-pentanediamine-succinate and construction method and application thereof | 中国科学院天津工业生物技术研究所 | 2022-05-31 | — | — | CN | disclosed |
| CN-109180494-B | Pentanediamine succinate and crystal thereof | 南京工业大学 | 2021-07-16 | — | — | CN | disclosed |
| CN-112852692-A | Recombinant escherichia coli for producing 1, 5-pentanediamine-succinate and construction method and application thereof | 中国科学院天津工业生物技术研究所 | 2021-05-28 | — | — | CN | disclosed |
| CN-112852692-A | Recombinant escherichia coli for producing 1, 5-pentanediamine-succinate and construction method and application thereof | 中国科学院天津工业生物技术研究所 | 2021-05-28 | — | — | CN | disclosed |
| CN-112852692-A | Recombinant escherichia coli for producing 1, 5-pentanediamine-succinate and construction method and application thereof | 中国科学院天津工业生物技术研究所 | 2021-05-28 | — | — | CN | disclosed |
| CN-108531494-B | Method for preparing bio-based nylon-54 precursor by co-fermentation of genetically engineered bacteria | 南京工业大学 | 2020-11-10 | — | — | CN | disclosed |
| CN-109180494-A | Pentanediamine succinate and crystal thereof | 南京工业大学 | 2019-01-11 | — | — | CN | disclosed |
| US-7189543-B2 | Method for producing cadaverine dicarboxylate | AJINOMOTO CO., INC. (JP) | 2007-03-13 | — | — | US | disclosed |
| EP-1482055-B1 | Method for producing cadaverine dicarboxylate and its use for the production of nylon | AJINOMOTO KK (JP) | 2006-03-01 | — | — | EP | disclosed |
| US-20050003497-A1 | Method for producing cadaverine dicarboxylate | AJINOMOTO CO., INC. (JP) | 2005-01-06 | — | — | US | disclosed |
| EP-1482055-A1 | Method for producing cadaverine dicarboxylate and its use for the production of nylon | Ajinomoto Co., Inc. (JP) | 2004-12-01 | — | — | EP | disclosed |