2-((Phenylimino)Methyl)Phenol

2-((Phenylimino)Methyl)Phenol

SCHEMBL5376364

Oc1ccccc1C=Nc1ccccc1.[Co]

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.84
CA12 O43570 7/20 0.64
CA2 P00918 7/20 0.64
CA9 Q16790 6/20 0.64
TSHR P16473 1/20 0.62
CA1 P00915 1/20 0.62
MAOB P27338 2/20 0.59
PABPC1 P11940 1/20 0.55
APOBEC3A P31941 1/20 0.55
APOBEC3G Q9HC16 1/20 0.55
KDM4E B2RXH2 2/20 0.53
MAPT P10636 3/20 0.52
ALDH1A1 P00352 2/20 0.52
GAA P10253 2/20 0.52
MEN1 O00255 1/20 0.52
HPGD P15428 1/20 0.52
GFER P55789 1/20 0.52
KMT2A Q03164 1/20 0.52
LMNA P02545 1/20 0.50
RAD52 P43351 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-((Phenylimino)Methyl)Phenol SCHEMBL5418701 1.00 SIRT2 (0.84) SIRT2CA12CA2CA9TSHR
2-((Phenylimino)Methyl)Phenol SCHEMBL347861 0.98 SIRT2 (0.88) SIRT2CA12CA2CA9TSHR
2-((Phenylimino)Methyl)Phenol SCHEMBL347862 0.98 SIRT2 (0.88) SIRT2CA12CA2CA9TSHR
2-((Phenylimino)Methyl)Phenol SCHEMBL29424118 0.98 SIRT2 (0.88) SIRT2CA12CA2CA9TSHR
2-((Phenylimino)Methyl)Phenol SCHEMBL27996307 0.96 SIRT2 (0.84) SIRT2CA12CA2CA9TSHR
2-((Phenylimino)Methyl)Phenol SCHEMBL1133042 0.96 SIRT2 (0.84) SIRT2CA12CA2CA9TSHR
2-((Phenylimino)Methyl)Phenol SCHEMBL453634 0.96 SIRT2 (0.84) SIRT2CA12CA2CA9TSHR
2-((Phenylimino)Methyl)Phenol SCHEMBL28071396 0.92 SIRT2 (0.78) SIRT2CA12CA2CA9TSHR
SCHEMBL2494084 0.91 SIRT2 (1.00) SIRT2CA12CA2CA9TSHR
SCHEMBL2494083 0.91 SIRT2 (1.00) SIRT2CA12CA2CA9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060069293-A1 Process for the preparation of alkylene glycols SAUDI BASIC INDUSTRIES CORPORATION 2006-03-30 US claimed
US-7161046-B2 Process for the preparation of alkylene glycols SAUDI BASIC INDUSTRIES CORPORATION (SA) 2007-01-09 US disclosed
US-20060069293-A1 Process for the preparation of alkylene glycols SAUDI BASIC INDUSTRIES CORPORATION 2006-03-30 US disclosed