SCHEMBL5376470

SCHEMBL5376470

COC(F)(F)C(F)(F)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9318338 0.80
SCHEMBL4578155 0.76 ALDH1A1 (0.39)
SCHEMBL247410 0.72
SCHEMBL7599106 0.71
SCHEMBL11801860 0.71
SCHEMBL8766236 0.69
SCHEMBL17123476 0.69 ALDH1A1 (0.33)
SCHEMBL9331248 0.69 ALDH1A1 (0.33)
SCHEMBL9931 0.69
SCHEMBL1760668 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115703698-B Preparation method of trifluoro vinyl alkyl ether compound and intermediate thereof 中国科学院上海有机化学研究所 2025-01-24 CN claimed
US-7247289-B2 Porous aluminum fluoride NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2007-07-24 US disclosed
US-20060025639-A1 Porous aluminum fluoride HENGDAO, QUAN (JP) 2006-02-02 US disclosed
JP-2002088006-A 1-CHLORO-1,1,2,2-TETRAFLUORO-2-METHOXYETHANE AND METHOD FOR PRODUCING THE SAME NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL & TECHNOLOGY 2002-03-27 JP disclosed
JP-2002088006-A 1-CHLORO-1,1,2,2-TETRAFLUORO-2-METHOXYETHANE AND METHOD FOR PRODUCING THE SAME NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL & TECHNOLOGY 2002-03-27 JP disclosed