SCHEMBL8766236

SCHEMBL8766236

FC(F)(Cl)C(F)(F)OC(F)(F)C(F)(F)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9391444 0.96
SCHEMBL9148413 0.89
SCHEMBL9231579 0.89
SCHEMBL21224996 0.87
SCHEMBL8968616 0.85
SCHEMBL9149051 0.80
SCHEMBL30900630 0.80
SCHEMBL9149386 0.80 LMNA (0.33)
SCHEMBL13131894 0.79
SCHEMBL31326552 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0646557-B1 Fluorination in tubular reactor system MINNESOTA MINING & MFG (US) 1997-08-13 EP disclosed
US-5578278-A TURBULENT FLUID FLOW MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-11-26 US disclosed
US-5488142-A Fluorination in tubular reactor system MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-01-30 US disclosed
EP-0646557-A1 Fluorination in tubular reactor system MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-05 EP disclosed
US-5399718-A Direct fluorination process for making perfluorinated organic substances MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-03-21 US disclosed
US-5362919-A Direct fluorination process for making perfluorinated organic substances MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-11-08 US disclosed
EP-0609200-A1 DIRECT FLUORINATION PROCESS FOR MAKING PERFLUORINATED ORGANIC SUBSTANCES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-08-10 EP disclosed
EP-0557167-A1 Preparation of fluorinated functional compounds MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-25 EP disclosed
WO-1990006296-A1 DIRECT FLUORINATION PROCESS FOR MAKING PERFLUORINATED ORGANIC SUBSTANCES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-06-14 WO disclosed
WO-1990003357-A1 PERFLUOROACETAL AND PERFLUOROKETAL COMPOUNDS AND USE THEREOF IN THERMAL SHOCK TESTING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-04-05 WO disclosed