SCHEMBL5376525

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11564651	0.77	ACLY (0.45)	MAPT
	SCHEMBL5380486	0.76	DPP4 (0.42)	DPP4
	SCHEMBL11563797	0.74	NPSR1 (0.37)	HTTMEN1KMT2ADPP4MAPT
	SCHEMBL11565348	0.73	TDP1 (0.37)	HTTKMT2ADPP4MAPT
	SCHEMBL11564013	0.72	DPP4 (0.40)	HTTKMT2ADPP4MAPT
	SCHEMBL11562253	0.72	TDP1 (0.36)	HTTKMT2ADPP4MAPT
	SCHEMBL11585145	0.72	DPP4 (0.48)	HTTKMT2ADPP4MAPT
	SCHEMBL11558968	0.72	CNR2 (0.37)	HTTKMT2ADPP4MAPT
	SCHEMBL11561717	0.72	CNR2 (0.36)	MAPT
	SCHEMBL11566911	0.72	DPP4 (0.39)	KDM4EMEN1KMT2AGAADPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.