Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.84 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 7/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 5/20 | 0.50 |
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oryzalin SCHEMBL55377 | 0.91 | TDP1 (1.00) | TDP1MAPTCYP3A4MAPK1PKM | |
| Oryzalin SCHEMBL8536571 | 0.91 | TDP1 (1.00) | TDP1MAPTCYP3A4MAPK1PKM | |
| Oryzalin SCHEMBL28500496 | 0.90 | TDP1 (0.97) | TDP1MAPTCYP3A4MAPK1PKM | |
| Oryzalin SCHEMBL28906635 | 0.90 | TDP1 (0.97) | TDP1MAPTCYP3A4MAPK1PKM | |
| SCHEMBL11576930 | 0.87 | TDP1 (0.63) | TDP1MAPTCYP3A4MAPK1PKM | |
| Nitralin SCHEMBL8338510 | 0.86 | TDP1 (0.89) | TDP1MAPTCYP3A4MAPK1PKM | |
| Benfluralin SCHEMBL10614193 | 0.85 | CYP3A4 (0.75) | TDP1MAPTCYP3A4MAPK1PKM | |
| Oryzalin SCHEMBL6950420 | 0.83 | TDP1 (0.82) | TDP1MAPTCYP3A4MAPK1PKM | |
| SCHEMBL12190303 | 0.82 | TDP1 (0.58) | TDP1MAPTCYP3A4MAPK1PKM | |
| SCHEMBL11808614 | 0.82 | MAPT (0.64) | TDP1MAPTCYP3A4MAPK1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050227982-A1 | Antileishmanial dinitroaniline sulfanomides with activity against parasite tubulin | WERBOVETZ KARL | 2005-10-13 | — | — | US | claimed |
| EP-1560574-A2 | ANTILEISHMANIAL DINITROANILINE SULFONAMIDES WITH ACTIVITY AGAINST PARASITE TUBULIN | THE OHIO STATE UNIVERSITY (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2003090678-A2 | ANTILEISHMANIAL DINITROANILINE SULFONAMIDES WITH ACTIVITY AGAINST PARASITE TUBULIN | OHIO STATE UNIVERSITY (US) | 2003-11-06 | — | — | WO | claimed |
| US-7211696-B2 | Antileishmanial dinitroaniline sulfanomides with activity against parasite tubulin | THE OHIO STATE UNIVERSITY (US) | 2007-05-01 | — | — | US | disclosed |
| US-20050227982-A1 | Antileishmanial dinitroaniline sulfanomides with activity against parasite tubulin | WERBOVETZ KARL | 2005-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050227982-A1 | Antileishmanial dinitroaniline sulfanomides with activity against parasite tubulin | TUBB, TUBB2A, TUBA1A | TDP1 2582/4885MAPT 1840/4885CYP3A4 3833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.