TUBB2A

Tubulin beta-2A chain · Q13885 · TUBB2A on Sugi Atlas →

134,016 patent compounds predicted against TUBB2A, 85,041 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Curacin A (SCHEMBL61304)	1.00	20/20
Vintriptol (SCHEMBL93959)	1.00	15/20
Vindesine (SCHEMBL4420)	0.85	13/20
Vindesine (SCHEMBL4421)	0.85	13/20
Vindesine (SCHEMBL4285)	0.85	12/20
SCHEMBL147173	0.50	12/20
SCHEMBL147174	0.50	12/20
Combretastatin (SCHEMBL19955)	1.00	9/20
Combretastatin (SCHEMBL19956)	1.00	9/20
SCHEMBL118593	0.69	9/20
Centaureidin (SCHEMBL9953)	1.00	8/20
Thiocolchicine (SCHEMBL43160)	1.00	8/20
Thiocolchicine (SCHEMBL43161)	1.00	8/20
SCHEMBL68067	0.62	8/20
Fosbretabulin (SCHEMBL66079)	0.61	8/20
Vinorelbine (SCHEMBL4765)	1.00	7/20
Combretastatin A4 (SCHEMBL18945)	1.00	7/20
Combretastatin A4 (SCHEMBL18946)	1.00	7/20
Levofloxacin Anhydrous (SCHEMBL15397)	0.98	7/20
Ofloxacin (SCHEMBL24373)	0.98	7/20

Clinical trials — most relevant to TUBB2A by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Comparative Analysis of the Efficacies in Neoadjuvant Chemotherapy of Breast Cancer	PHASE3	COMPLETED
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU)	PHASE2/PHASE3	ACTIVE_NOT_RECRUITING
Vinorelbine in Relapsed Platinum Resistant or Refractory C5 High Grade Serous, Endometrioid, or Undifferentiated Primary Peritoneum, Fallopian Tube or Ovarian Cancer	PHASE2	UNKNOWN
A Multicenter Study of NAP (AL-108) in Schizophrenia	PHASE2	COMPLETED
Biologic Correlative Taxotere/AC	PHASE2	COMPLETED
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Esophageal Cancer	PHASE2	COMPLETED
Neoadjuvant Paclitaxel Plus Epirubicin Versus Vinorelbine Plus Epirubicin in Breast Cancer With TEKT4 Variations	PHASE2	COMPLETED
Study of ABT-751 in Patients With Refractory Hematologic Malignancies	PHASE1	COMPLETED
Treating Patients With Advanced Solid Tumors, Breast Cancer or Recurrent Ovarian Cancer	PHASE1	COMPLETED
SB-715992 in Treating Patients With Acute Leukemia, Chronic Myelogenous Leukemia, or Advanced Myelodysplastic Syndromes	PHASE1	COMPLETED
Phase I Study of Oral BAY 1217389 in Combination With Intravenous Paclitaxel	PHASE1	COMPLETED
Exploratory Evaluation of [11C]MPC6827	EARLY_PHASE1	COMPLETED
Diagnostic of Chemotherapy Induced Neuropathy in Children	nan	COMPLETED
Prostate Cancer Antigen 3 (PCA-3) Gene Project	nan	COMPLETED
CRF vs WCRF or PRF-DRG in CLBP of FJ Origin and RFA Failure of MBDR: Central Sensitization and Aberrant Nerve Sprouting	nan	UNKNOWN
Generating Intervals of Reference FFor Early Life Brain Biomarkers.	nan	RECRUITING
Effect of Low Dose of Colchicine on Platelet Reactivity	nan	COMPLETED
Mapping Disease Pathways for Biliary Atresia	nan	RECRUITING
The Relation of Microtubule-Associated Protein 2 and Cell Migration	nan	UNKNOWN
Diagnosis of Primary Ciliary Dyskinesia	nan	COMPLETED
Genetic Study of Patients With Primary Ciliary Dyskinesia	nan	COMPLETED
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM)	nan	COMPLETED
Myotubular Myopathy Genetic Testing Study	nan	COMPLETED
Association Between Luminal Bile Salt Content and Duodenal Mucosal Integrity in Functional Dyspepsia	nan	COMPLETED
Importance of the Microtubule Cytoskeleton in Oocyte Competence	nan	COMPLETED
Predicting Postoperative Delirium Using EEG, Genetics and Neurobiomarkers of Cerebral Injury	nan	COMPLETED
Gene Analysis of Parkinson's Disease	nan	COMPLETED
Neurorehabilitation in Patients With Disorders of Consciousness: Multidimensional Ambispective Study on the Impact of Single and Combined Approaches	nan	RECRUITING
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease	nan	RECRUITING
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants.	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a TUBB2A binder may also engage these)

Protein	Name	Similarity
P85108	—	1.000	P85108 →
TUBB2B	Tubulin beta-2B chain	1.000	landscape →
Q6B856	—	1.000	Q6B856 →
P11833	—	1.000	P11833 →
P68372	—	1.000	P68372 →
P69893	—	1.000	P69893 →
Q3MHM5	—	1.000	Q3MHM5 →
Q27U48	—	1.000	Q27U48 →
Q6GLE7	—	1.000	Q6GLE7 →
O44388	—	1.000	O44388 →
P46265	—	1.000	P46265 →
Q2HJ81	—	1.000	Q2HJ81 →
Q7TMM9	—	1.000	Q7TMM9 →
P12456	—	1.000	P12456 →
Q4R4X8	—	1.000	Q4R4X8 →
Q4R5B3	—	1.000	Q4R5B3 →
O59837	—	1.000	O59837 →
P61858	—	1.000	P61858 →
P02554	—	1.000	P02554 →
P30883	—	1.000	P30883 →
P33127	—	1.000	P33127 →
P32882	—	1.000	P32882 →
Q5R943	—	1.000	Q5R943 →
P09203	—	1.000	P09203 →
P14140	—	1.000	P14140 →
Q91240	—	1.000	Q91240 →
Q9YHC3	—	1.000	Q9YHC3 →
Q24560	—	1.000	Q24560 →
Q91575	—	1.000	Q91575 →
Q7JJU6	—	1.000	Q7JJU6 →