Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693697 | 0.88 | LMNA (0.51) | LMNACYP2D6CYP3A4ALDH1A1CYP2C9 | |
| Mephentermine SCHEMBL121178 | 0.79 | LMNA (1.00) | LMNACYP2D6CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL9275889 | 0.77 | LMNA (0.55) | LMNACYP2D6CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL8613504 | 0.77 | LMNA (0.65) | LMNACYP2D6CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL5255109 | 0.76 | LMNA (0.59) | LMNACYP2D6CYP3A4ALDH1A1CYP2C9 | |
| Mephentermine SCHEMBL3256311 | 0.73 | LMNA (0.78) | LMNACYP2D6CYP3A4ALDH1A1CYP2C9 | |
| Mephentermine SCHEMBL121177 | 0.73 | LMNA (0.78) | LMNACYP2D6CYP3A4ALDH1A1CYP2C9 | |
| Mephentermine SCHEMBL6237301 | 0.73 | LMNA (0.78) | LMNACYP2D6CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL5397874 | 0.72 | CYP2D6 (0.65) | LMNACYP2D6CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL5948337 | 0.72 | CYP3A4 (0.67) | LMNACYP2D6CYP3A4ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |