SCHEMBL5377204

SCHEMBL5377204

CCc1nnn(CCC#N)n1.NP(O)O

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.49
LMNA P02545 1/20 0.42
ATM Q13315 1/20 0.39
MAOB P27338 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20844627 0.74 KMT2A (0.45) KMT2ALMNAATMMAOB
SCHEMBL10242307 0.73 CNR2 (0.51) KMT2ALMNAATM
SCHEMBL1304700 0.71 LTA4H (0.44) KMT2ALMNAATM
SCHEMBL4413215 0.70 RECQL (0.42) KMT2ALMNAATM
SCHEMBL19221411 0.70 KMT2A (0.51) KMT2ALMNAATMMAOB
Hydrochloric Acid SCHEMBL3711535 0.70 LTA4H (0.42) KMT2ALMNAATM
SCHEMBL17627008 0.70 KMT2A (0.47) KMT2ALMNAATMMAOB
SCHEMBL4414619 0.68 KMT2A (0.39) KMT2AATM
SCHEMBL1324895 0.68 PKM (0.34) KMT2AATM
SCHEMBL4412024 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7205399-B1 Methods and reagents for oligonucleotide synthesis SIRNA THERAPEUTICS, INC. (US) 2007-04-17 US disclosed