Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | PKM | P14618 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.63 |
| ▸ | RELA | Q04206 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CASR | P41180 | 1/20 | 0.52 |
| ▸ | TNF | P01375 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5371056 | 1.00 | SMN1; SMN2 (0.63) | SMN1; SMN2KDM4EALDH1A1PKMNPC1 | |
| SCHEMBL5374092 | 1.00 | SMN1; SMN2 (0.63) | SMN1; SMN2KDM4EALDH1A1PKMNPC1 | |
| SCHEMBL5381431 | 1.00 | SMN1; SMN2 (0.63) | SMN1; SMN2KDM4EALDH1A1PKMNPC1 | |
| SCHEMBL5009001 | 0.91 | HPGD (0.70) | SMN1; SMN2KDM4EALDH1A1PKMNPC1 | |
| SCHEMBL5374437 | 0.88 | KDM4E (0.68) | SMN1; SMN2KDM4EALDH1A1PKMRAB9A | |
| SCHEMBL9348025 | 0.85 | LMNA (0.58) | KDM4EPKMNPC1RAB9AHPGD | |
| SCHEMBL5373120 | 0.85 | KDM4E (0.72) | SMN1; SMN2KDM4EALDH1A1PKMRAB9A | |
| SCHEMBL501617 | 0.85 | HPGD (0.84) | SMN1; SMN2KDM4EALDH1A1PKMNPC1 | |
| SCHEMBL501667 | 0.85 | HPGD (0.84) | SMN1; SMN2KDM4EALDH1A1PKMNPC1 | |
| SCHEMBL5377582 | 0.85 | HPGD (0.84) | SMN1; SMN2KDM4EALDH1A1PKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7252925-B2 | Nitrogen-containing organic compound, resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |
| US-20050095533-A1 | Nitrogen-containing organic compound, resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. | 2005-05-05 | — | — | US | disclosed |