⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3833402 | 1.00 | — | — | |
| SCHEMBL5711263 | 0.60 | GABRA5 (0.37) | — | |
| SCHEMBL6835640 | 0.60 | GABRA5 (0.37) | — | |
| SCHEMBL1651480 | 0.60 | FFAR3 (0.31) | — | |
| SCHEMBL5711305 | 0.58 | GABRA5 (0.56) | — | |
| SCHEMBL17501779 | 0.58 | FFAR3 (0.30) | — | |
| SCHEMBL1226097 | 0.58 | — | — | |
| SCHEMBL4314064 | 0.58 | — | — | |
| SCHEMBL1982906 | 0.56 | — | — | |
| SCHEMBL351951 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294718-B2 | Synthesis of a 4-methylthiazole-4(S)-carboxylic acid compound | GENZYME CORPORATION (US) | 2007-11-13 | — | — | US | disclosed |
| EP-1529037-A2 | SYNTHESIS OF 2-ALKYLCYSTEINES, 2-(HYDROXYLATED PHENYL)-4-ALKYLTHIAZOLINE-4-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | Genzyme Corporation (US) | 2005-05-11 | — | — | EP | disclosed |
| US-6861532-B2 | Synthesis of 2-alkylcysteine | GENZYME CORPORATION (US) | 2005-03-01 | — | — | US | disclosed |
| US-20030229231-A1 | Synthesis of 2-alkylcysteine | GENZYME CORPORATION | 2003-12-11 | — | — | US | disclosed |
| WO-2003097622-A2 | SYNTHESIS OF 2-ALKYLCYSTEINES, 2-(HYDROXYLATED PHENYL)-4-ALKYLTHIAZOLINE-4-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | GENZYME CORPORATION (US) | 2003-11-27 | — | — | WO | disclosed |