Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 8/20 | 0.68 |
| ▸ | TEK | Q02763 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5388028 | 0.82 | GSK3B (0.66) | GSK3BMAPK14KDM4EHPGDHSD17B10 | |
| SCHEMBL5381549 | 0.81 | GSK3B (1.00) | GSK3BMAPK14HPGDHSD17B10CDC7 | |
| SCHEMBL5377580 | 0.80 | GSK3B (0.87) | GSK3BHPGDHSD17B10CDC7XDH | |
| SCHEMBL801881 | 0.80 | GSK3B (0.63) | GSK3BTEKHPGDCDC7 | |
| SCHEMBL5380569 | 0.78 | GSK3B (0.73) | GSK3BMAPK14KDM4ECDC7KMT2A | |
| SCHEMBL5383553 | 0.78 | GSK3B (0.72) | GSK3BMAPK14KMT2AXDH | |
| SCHEMBL5378011 | 0.78 | TEK (0.47) | TEKMAPK14HPGDCDC7SMN1; SMN2 | |
| SCHEMBL5396525 | 0.77 | GSK3B (0.71) | GSK3BKDM4EHPGDCDC7KMT2A | |
| SCHEMBL5380266 | 0.76 | GSK3B (0.74) | GSK3BCDC7KMT2AXDHSMN1; SMN2 | |
| SCHEMBL5377975 | 0.76 | GSK3B (1.00) | GSK3BCDC7XDHSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115721-B1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEM CORP (JP) | 2003-12-10 | — | — | EP | claimed |
| CN-1328552-A | Pyrimidone derivatives | MITSUBISHI CHEM CORP (JP) | 2001-12-26 | — | — | CN | claimed |
| EP-1115721-A1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-18 | — | — | EP | claimed |
| WO-2000018758-A1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-04-06 | — | — | WO | claimed |
| US-7256199-B1 | Pyrimidone derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-08-14 | — | — | US | disclosed |
| EP-1115721-B1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEM CORP (JP) | 2003-12-10 | — | — | EP | disclosed |
| EP-1115721-A1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018758-A1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-04-06 | — | — | WO | disclosed |