Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 0.72 |
| ▸ | XDH | P47989 | 1/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.52 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.52 |
| ▸ | CSNK1E | P49674 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5380569 | 0.84 | GSK3B (0.73) | GSK3BMAPK14CSNK1DNPC1RAB9A | |
| SCHEMBL5381549 | 0.84 | GSK3B (1.00) | GSK3BXDHMAPK14 | |
| SCHEMBL5377580 | 0.83 | GSK3B (0.87) | GSK3BXDHCSNK1D | |
| SCHEMBL7391408 | 0.83 | GSK3B (0.72) | GSK3BXDHNPC1RAB9AKMT2A | |
| SCHEMBL5392045 | 0.83 | GSK3B (0.72) | GSK3BXDHMAPK14CSNK1DNPC1 | |
| SCHEMBL5391583 | 0.83 | GSK3B (0.67) | GSK3BMAPK14NPC1RAB9A | |
| SCHEMBL5388178 | 0.80 | GSK3B (0.67) | GSK3BXDHMAPK14 | |
| SCHEMBL5376063 | 0.80 | GSK3B (0.76) | GSK3BNPC1RAB9AKMT2A | |
| SCHEMBL5386532 | 0.80 | GSK3B (0.62) | GSK3BMAPK14NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5386672 | 0.79 | GSK3B (0.61) | GSK3BXDHMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115721-B1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEM CORP (JP) | 2003-12-10 | — | — | EP | claimed |
| CN-1328552-A | Pyrimidone derivatives | MITSUBISHI CHEM CORP (JP) | 2001-12-26 | — | — | CN | claimed |
| EP-1115721-A1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-18 | — | — | EP | claimed |
| WO-2000018758-A1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-04-06 | — | — | WO | claimed |
| US-7256199-B1 | Pyrimidone derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-08-14 | — | — | US | disclosed |
| EP-1115721-B1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEM CORP (JP) | 2003-12-10 | — | — | EP | disclosed |
| EP-1115721-A1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018758-A1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-04-06 | — | — | WO | disclosed |