Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14830816 | 0.88 | MEN1 (0.47) | ROCK2HSD17B10MEN1GFERKMT2A | |
| SCHEMBL6626168 | 0.86 | MEN1 (0.47) | ROCK2MEN1GFERKMT2AKCNQ3 | |
| SCHEMBL6858656 | 0.86 | MEN1 (0.47) | ROCK2MEN1GFERKMT2AKCNQ3 | |
| SCHEMBL782021 | 0.86 | MEN1 (0.47) | ROCK2MEN1GFERKMT2AKCNQ3 | |
| SCHEMBL6645521 | 0.83 | CYP3A4 (0.60) | ROCK2MEN1GFERKMT2AKCNQ3 | |
| SCHEMBL3978842 | 0.83 | CYP3A4 (0.60) | ROCK2MEN1GFERKMT2AKCNQ3 | |
| SCHEMBL14848269 | 0.81 | BACE1 (0.50) | MEN1GFERKMT2AKCNQ3KCNQ2 | |
| SCHEMBL18869978 | 0.81 | BACE1 (0.50) | MEN1GFERKMT2AKCNQ3KCNQ2 | |
| SCHEMBL5863237 | 0.80 | AOC3 (0.47) | ROCK2HSD17B10MEN1GFERKMT2A | |
| SCHEMBL5863244 | 0.80 | AOC3 (0.47) | ROCK2HSD17B10MEN1GFERKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1790650-A1 | NOVEL SUBSTITUTED IMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-05-30 | — | — | EP | disclosed |