⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28655760 | 0.90 | — | — | |
| SCHEMBL4949941 | 0.87 | LMNA (0.44) | — | |
| SCHEMBL4952250 | 0.79 | — | — | |
| SCHEMBL15291832 | 0.76 | — | — | |
| SCHEMBL451416 | 0.75 | — | — | |
| SCHEMBL17333407 | 0.75 | — | — | |
| SCHEMBL12967670 | 0.75 | — | — | |
| SCHEMBL6879900 | 0.75 | — | — | |
| SCHEMBL4019339 | 0.73 | — | — | |
| SCHEMBL14369099 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3212620-B1 | PROCESS FOR THE PREPARATION OF APIXABAN AND INTERMEDIATES THEREOF | JUBILANT GENERICS LTD FORMERLY JUBILANT LIFE SCIENCES DIVISION (IN) | 2020-11-25 | — | — | EP | disclosed |
| US-9932336-B2 | Process for the preparation of apixaban and intermediates thereof | Jubilant Generics Limited (IN) | 2018-04-03 | — | — | US | disclosed |
| US-20170313699-A1 | PROCESS FOR THE PREPARATION OF APIXABAN AND INTERMEDIATES THEREOF | Jubilant Generics Limited (IN) | 2017-11-02 | — | — | US | disclosed |
| EP-3212620-A1 | PROCESS FOR THE PREPARATION OF APIXABAN AND INTERMEDIATES THEREOF | Jubilant Generics Limited (Formerly Jubilant Life Sciences Division) (IN) | 2017-09-06 | — | — | EP | disclosed |
| WO-2016067308-A1 | PROCESS FOR THE PREPARATION OF APIXABAN AND INTERMEDIATES THEREOF | JUBILANT GENERICS LIMITED (FORMERLY JUBILANT LIFE SCIENCES DIVISION) (IN) | 2016-05-06 | — | — | WO | disclosed |
| US-7189389-B2 | Pharmaceutical composition of human interferon-α2 and interferon α8 subtypes | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2007-03-13 | — | — | US | disclosed |
| US-20040197307-A1 | Expression enhancer for protein synthesis inhibitory genes | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2004-10-07 | — | — | US | disclosed |
| US-6773701-B2 | AN GENE EXPRESSION ENHANCER COMPRISING A MIXTURE OF HUMAN INTERFERON- ALPHA 2 AND INTERFERON- ALPHA 8 SUBTYPES | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2004-08-10 | — | — | US | disclosed |
| EP-1329223-A1 | EXPRESSION POTENTIATOR FOR PROTEIN SYNTHESIS REGULATORY GENE | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-20030039629-A1 | Espression enhancer for protein synthesis inhibitory genes | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2003-02-27 | — | — | US | disclosed |