Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfanilamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.68 |
| ▸ | CA1 | P00915 | 17/20 | 0.68 |
| ▸ | CA12 | O43570 | 14/20 | 0.68 |
| ▸ | CA9 | Q16790 | 14/20 | 0.68 |
| ▸ | CA7 | P43166 | 9/20 | 0.68 |
| ▸ | CA14 | Q9ULX7 | 7/20 | 0.68 |
| ▸ | CA4 | P22748 | 7/20 | 0.68 |
| ▸ | CA5A | P35218 | 6/20 | 0.68 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.68 |
| ▸ | CA6 | P23280 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mafenide SCHEMBL11664949 | 0.90 | CA2 (0.83) | CA2CA1CA12CA9CA7 | |
| Sulfanilamide SCHEMBL27483111 | 0.87 | CA1 (0.72) | CA2CA1CA12CA9CA7 | |
| Dapsone SCHEMBL4106701 | 0.85 | CA2 (0.74) | CA2CA1CA12CA9CA7 | |
| Sulfanilamide SCHEMBL27911829 | 0.84 | CA2 (0.81) | CA2CA1CA12CA9CA7 | |
| Sulfanilamide SCHEMBL8380125 | 0.84 | CA2 (0.81) | CA2CA1CA12CA9CA7 | |
| Sulfanilamide SCHEMBL8449748 | 0.84 | CA2 (0.90) | CA2CA1CA12CA9CA7 | |
| Sulfanilamide SCHEMBL28069325 | 0.84 | CA2 (0.69) | CA2CA1CA12CA9CA7 | |
| P-Toluenesulfonamide SCHEMBL28234027 | 0.84 | CA1 (0.66) | CA2CA1CA12CA9CA7 | |
| Mafenide SCHEMBL9295695 | 0.82 | CA2 (1.00) | CA2CA1CA12CA9CA7 | |
| Mafenide SCHEMBL41628 | 0.82 | CA2 (1.00) | CA2CA1CA12CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070080622-A1 | Method for forming phosphor screen with metal back | KABUSHIKI KAISHA TOSHIBA (JP) | 2007-04-12 | — | — | US | claimed |
| EP-1691390-A1 | METHOD FOR FORMING PHOSPHOR SCREEN WITH METAL BACK | Kabushiki Kaisha Toshiba (JP) | 2006-08-16 | — | — | EP | claimed |
| US-6841926-B2 | Transfer film, method for forming metal back layer, and image display | KABUSHIKI KAISHA TOSHIBA (JP) | 2005-01-11 | — | — | US | claimed |
| US-20030006696-A1 | Transfer film, method for forming metal back layer, and image display | FUJI PIGMENT CO., LTD. (JP) | 2003-01-09 | — | — | US | claimed |
| EP-1255275-A1 | TRANSFER FILM, METHOD FOR FORMING METAL BACK LAYER, AND IMAGE DISPLAY | Kabushiki Kaisha Toshiba (JP) | 2002-11-06 | — | — | EP | claimed |
| CN-105378075-B | Histidyl-TRNA synthetase-FC conjugates | ATYR 医药公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-105636592-A | Pro-drug forming compounds | EVESTRA INC | 2016-06-01 | — | — | CN | disclosed |
| US-20070080622-A1 | Method for forming phosphor screen with metal back | KABUSHIKI KAISHA TOSHIBA (JP) | 2007-04-12 | — | — | US | disclosed |
| US-7157843-B2 | Transfer film, method for forming metal back layer, and display device | KABUSHIKI KAISHA TOSHIBA (JP) | 2007-01-02 | — | — | US | disclosed |
| EP-1691390-A1 | METHOD FOR FORMING PHOSPHOR SCREEN WITH METAL BACK | Kabushiki Kaisha Toshiba (JP) | 2006-08-16 | — | — | EP | disclosed |
| US-20050062394-A1 | Transfer film, method for forming metal back layer, and display device | KABUSHIKI KAISHA TOSHIBA (JP) | 2005-03-24 | — | — | US | disclosed |
| US-6841926-B2 | Transfer film, method for forming metal back layer, and image display | KABUSHIKI KAISHA TOSHIBA (JP) | 2005-01-11 | — | — | US | disclosed |
| US-20030006696-A1 | Transfer film, method for forming metal back layer, and image display | FUJI PIGMENT CO., LTD. (JP) | 2003-01-09 | — | — | US | disclosed |
| EP-1255275-A1 | TRANSFER FILM, METHOD FOR FORMING METAL BACK LAYER, AND IMAGE DISPLAY | Kabushiki Kaisha Toshiba (JP) | 2002-11-06 | — | — | EP | disclosed |