Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | PPM1D | O15297 | 2/20 | 0.36 |
| ▸ | GSR | P00390 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464146 | 1.00 | NPY1R (0.38) | NPY1RNPY2RNPY4RNPY5RPPM1D | |
| SCHEMBL7464139 | 1.00 | NPY1R (0.38) | NPY1RNPY2RNPY4RNPY5RPPM1D | |
| SCHEMBL5380480 | 1.00 | NPY1R (0.38) | NPY1RNPY2RNPY4RNPY5RPPM1D | |
| SCHEMBL5380472 | 1.00 | NPY1R (0.38) | NPY1RNPY2RNPY4RNPY5RPPM1D | |
| SCHEMBL13573044 | 0.96 | NPY1R (0.41) | NPY1RNPY2RNPY4RNPY5RPPM1D | |
| SCHEMBL13573075 | 0.94 | NPY1R (0.40) | NPY1RNPY2RNPY4RNPY5RPPM1D | |
| SCHEMBL13573064 | 0.94 | NPY1R (0.40) | NPY1RNPY2RNPY4RNPY5RPPM1D | |
| SCHEMBL1989059 | 0.89 | PPM1D (0.35) | NPY1RNPY2RNPY4RNPY5RPPM1D | |
| SCHEMBL18049618 | 0.89 | PPM1D (0.35) | NPY1RNPY2RNPY4RNPY5RPPM1D | |
| SCHEMBL1989437 | 0.89 | PPM1D (0.35) | NPY1RNPY2RNPY4RNPY5RPPM1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | ELI LILLY AND COMPANY | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | NCOA4, PPARG, PPARA | NPY1R 508/4885NPY2R 227/4885NPY4R 47/4885 |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | PPARG, NCOA4, PPARA | NPY1R 574/4885NPY2R 303/4885NPY4R 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.