Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | PPM1D | O15297 | 2/20 | 0.36 |
| ▸ | GSR | P00390 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464139 | 1.00 | NPY1R (0.38) | NPY1RNPY2RNPY4RNPY5RPPM1D | |
| SCHEMBL5380480 | 1.00 | NPY1R (0.38) | NPY1RNPY2RNPY4RNPY5RPPM1D | |
| SCHEMBL5380472 | 1.00 | NPY1R (0.38) | NPY1RNPY2RNPY4RNPY5RPPM1D | |
| SCHEMBL5380476 | 1.00 | NPY1R (0.38) | NPY1RNPY2RNPY4RNPY5RPPM1D | |
| SCHEMBL13573044 | 0.96 | NPY1R (0.41) | NPY1RNPY2RNPY4RNPY5RPPM1D | |
| SCHEMBL13573075 | 0.94 | NPY1R (0.40) | NPY1RNPY2RNPY4RNPY5RPPM1D | |
| SCHEMBL13573064 | 0.94 | NPY1R (0.40) | NPY1RNPY2RNPY4RNPY5RPPM1D | |
| SCHEMBL1989059 | 0.89 | PPM1D (0.35) | NPY1RNPY2RNPY4RNPY5RPPM1D | |
| SCHEMBL18049618 | 0.89 | PPM1D (0.35) | NPY1RNPY2RNPY4RNPY5RPPM1D | |
| SCHEMBL1989437 | 0.89 | PPM1D (0.35) | NPY1RNPY2RNPY4RNPY5RPPM1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5733882-A | Retroviral protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-31 | — | — | US | disclosed |
| EP-0602069-A4 | RETROVIRAL PROTEASE INHIBITORS. | SMITHKLINE BEECHAM CORP (US) | 1995-05-03 | — | — | EP | disclosed |
| EP-0602069-A1 | RETROVIRAL PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-06-22 | — | — | EP | disclosed |
| WO-1993002057-A1 | RETROVIRAL PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-04 | — | — | WO | disclosed |