Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.68 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.68 |
| ▸ | MAOA | P21397 | 1/20 | 0.68 |
| ▸ | DRD1 | P21728 | 1/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.68 |
| ▸ | HTR2B | P41595 | 1/20 | 0.68 |
| ▸ | CCR2 | P41597 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | MIF | P14174 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1997655 | 0.90 | ALDH1A1 (0.75) | ALDH1A1CYP3A4HPGDTDP1ABCB11 | |
| SCHEMBL2976682 | 0.87 | ALDH1A1 (0.55) | ALDH1A1CYP3A4HPGDTDP1ABCB11 | |
| SCHEMBL6390165 | 0.87 | ALDH1A1 (0.55) | ALDH1A1CYP3A4HPGDTDP1ABCB11 | |
| SCHEMBL6392900 | 0.87 | CYP1A2 (0.55) | ALDH1A1CYP3A4HPGDTDP1ABCB11 | |
| SCHEMBL3205617 | 0.84 | ALDH1A1 (0.52) | ALDH1A1CYP3A4HPGDTDP1ABCB11 | |
| SCHEMBL29825554 | 0.82 | ALDH1A1 (0.50) | ALDH1A1CYP3A4HPGDTDP1ABCB11 | |
| SCHEMBL6395292 | 0.82 | ALDH1A1 (0.50) | ALDH1A1CYP3A4HPGDTDP1ABCB11 | |
| SCHEMBL592754 | 0.82 | ALDH1A1 (0.50) | ALDH1A1CYP3A4HPGDTDP1ABCB11 | |
| 1-Naphthylisothiocyanate SCHEMBL29354904 | 0.81 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HPGDTDP1ABCB11 | |
| 1-Naphthylisothiocyanate SCHEMBL419795 | 0.81 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HPGDTDP1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11648319-B2 | rAAV with chemically modified capsid | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2023-05-16 | — | — | US | disclosed |
| US-20220193252-A1 | RAAV WITH CHEMICALLY MODIFIED CAPSID | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2022-06-23 | — | — | US | disclosed |
| US-20210205467-A1 | RAAV WITH CHEMICALLY MODIFIED CAPSID | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2021-07-08 | — | — | US | disclosed |
| US-7214762-B1 | Redox-active polymer and electrode comprising the same | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2007-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210205467-A1 | RAAV WITH CHEMICALLY MODIFIED CAPSID | IGF2R, CFH, M6PR | ALDH1A1 174/4885CYP3A4 2960/4885HPGD 4633/4885 |
| US-11648319-B2 | rAAV with chemically modified capsid | IGF2R, CFH, M6PR | ALDH1A1 174/4885CYP3A4 2960/4885HPGD 4633/4885 |
| US-20220193252-A1 | RAAV WITH CHEMICALLY MODIFIED CAPSID | CFH, IGF2R, M6PR | ALDH1A1 191/4885CYP3A4 2855/4885HPGD 4718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.