SCHEMBL538186

SCHEMBL538186

C=Cc1c[nH]c(C=CC(=O)O)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.42
BLM P54132 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
CYP3A4 P08684 1/20 0.42
TSHR P16473 1/20 0.42
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
HCAR2 Q8TDS4 2/20 0.33
HDAC3 O15379 1/20 0.33
TNKS O95271 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC10 Q969S8 1/20 0.33
HDAC11 Q96DB2 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
HDAC9 Q9UKV0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9326981 0.87 KDM4E (0.46) KDM4EBLMNPSR1CYP3A4TSHR
SCHEMBL1329846 0.71 KDM4E (0.41) KDM4EBLMNPSR1CYP3A4TSHR
SCHEMBL30198493 0.71 LMNA (0.31) LMNA
SCHEMBL2913701 0.70 MAP3K7 (0.30) MAP3K7TAB1
SCHEMBL27915573 0.70 ALDH1A1 (0.38) KDM4ECYP3A4TSHRALDH1A1NFKB1
SCHEMBL1650784 0.70 MAPT (0.44) KDM4EBLMNPSR1CYP3A4TSHR
SCHEMBL8993182 0.68
SCHEMBL1902161 0.68 KDM4E (0.41) KDM4EBLMNPSR1CYP3A4TSHR
SCHEMBL31324241 0.68 KDM4E (0.41) KDM4EBLMNPSR1CYP3A4TSHR
SCHEMBL6181311 0.68 KDM4E (0.41) KDM4EBLMNPSR1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105148750-B A kind of method that polyamide composite film surface is modified 浙江大学 2017-07-28 CN claimed
CN-105603454-B The production method and electrolysis additive of a kind of electrolytic manganese metal 吉首大学 2018-03-27 CN disclosed
CN-105148750-B A kind of method that polyamide composite film surface is modified 浙江大学 2017-07-28 CN disclosed
CN-102867648-A Vinylimidazole segment-containing polymer gel electrolyte and preparation method and application thereof UNIV EAST CHINA NORMAL 2013-01-09 CN disclosed
US-8148315-B2 Method for uniform deposition of fabric care actives in a non-aqueous fabric treatment system THE PROCTER & GAMBLE COMPANY (US) 2012-04-03 US disclosed
EP-1639075-B1 DELIVERY SYSTEM FOR UNIFORM DEPOSITION OF FABRIC CARE ACTIVES IN A NON-AQUEOUS FABRIC TREATMENT SYSTEM PROCTER & GAMBLE (US) 2012-02-08 EP disclosed
US-7462589-B2 Delivery system for uniform deposition of fabric care actives in a non-aqueous fabric treatment system THE PROCTER & GAMBLE COMPANY (US) 2008-12-09 US disclosed
US-7300593-B2 Process for purifying a lipophilic fluid THE PROCTER & GAMBLE COMPANY (US) 2007-11-27 US disclosed
US-7300594-B2 Process for purifying a lipophilic fluid by modifying the contaminants THE PROCTER & GAMBLE COMPANY (US) 2007-11-27 US disclosed
US-7053033-B2 Treatment of fabric articles with specific fabric care actives and a siloxane lipophilic fluid PROCTER & GAMBLE COMPANY (US) 2006-05-30 US disclosed
WO-2005003442-A1 PROCESS FOR PURIFYING A LIPOPHILIC FLUID THE PROCTER & GAMBLE COMPANY (US) 2005-01-13 WO disclosed
US-20050009724-A1 Process for purifying a lipophilic fluid THE PROCTER & GAMBLE COMPANY 2005-01-13 US disclosed
US-20050000027-A1 Delivery system for uniform deposition of fabric care actives in a non-aqueous fabric treatment system PROCTER & GAMBLE COMPANY, THE 2005-01-06 US disclosed
US-20050000029-A1 Process for purifying a lipophilic fluid by modifying the contaminants THE PROCTER & GAMBLE COMPANY 2005-01-06 US disclosed
US-20050000028-A1 Method for uniform deposition of fabric care actives in a non-aqueous fabric treatment system PROCTER & GAMBLE COMPANY, THE 2005-01-06 US disclosed
EP-1463857-A1 TREATMENT OF FABRIC ARTICLES WITH SPECIFIC FABRIC CARE ACTIVES THE PROCTER & GAMBLE COMPANY (US) 2004-10-06 EP disclosed
US-20040142839-A1 TREATMENT OF FABRIC ARTICLES WITH SPECIFIC FABRIC CARE ACTIVES THE PROCTER & GAMBLE COMPANY 2004-07-22 US disclosed
US-6734153-B2 APPLYING LIPOPHILIC FLUID TO FABRICS PROCTER & GAMBLE COMPANY 2004-05-11 US disclosed
WO-2003054281-A1 TREATMENT OF FABRIC ARTICLES WITH SPECIFIC FABRIC CARE ACTIVES THE PROCTER & GAMBLE COMPANY (US) 2003-07-03 WO disclosed
US-20030119709-A1 Treatment of fabric articles with specific fabric care actives THE PROCTER & GAMBLE COMAPANY 2003-06-26 US disclosed