Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986558 | 0.90 | FFAR1 (0.41) | FFAR1CA2PPARGPIM3PIM2 | |
| SCHEMBL5390713 | 0.86 | FFAR1 (0.52) | FFAR1PPARGRARGRXRAAOC3 | |
| SCHEMBL5397263 | 0.86 | FFAR1 (0.52) | FFAR1PPARGRARGRXRAAOC3 | |
| SCHEMBL5383052 | 0.83 | FFAR1 (0.40) | FFAR1CA2PPARGLTB4RTDP1 | |
| SCHEMBL5760347 | 0.83 | FFAR1 (0.47) | FFAR1CA2PPARGPIM3PIM2 | |
| SCHEMBL27599885 | 0.81 | FFAR1 (0.39) | FFAR1CA2PPARGPIM3PIM2 | |
| SCHEMBL27599883 | 0.79 | FFAR1 (0.44) | FFAR1CA2PPARGPIM3PIM2 | |
| SCHEMBL5763775 | 0.78 | FFAR1 (0.53) | FFAR1PPARGRARGRXRAAOC3 | |
| SCHEMBL5762681 | 0.78 | FFAR1 (0.53) | FFAR1PPARGRARGRXRAAOC3 | |
| SCHEMBL5397356 | 0.77 | FFAR1 (0.52) | FFAR1PPARGRARGRXRAAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294639-B2 | Biaromatic ligand activators of PPARγ receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-11-13 | — | — | US | disclosed |