Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 7/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27599883 | 0.87 | FFAR1 (0.44) | FFAR1CA2PPARGPIM3PIM2 | |
| SCHEMBL6992217 | 0.86 | PPARG (0.41) | FFAR1CA2PPARGALDH1A1 | |
| SCHEMBL6986558 | 0.85 | FFAR1 (0.41) | FFAR1CA2PPARGPIM3PIM2 | |
| SCHEMBL7523244 | 0.83 | FFAR1 (0.43) | FFAR1CA2PPARGPTPN1 | |
| SCHEMBL27599885 | 0.83 | FFAR1 (0.39) | FFAR1CA2PPARGPIM3PIM2 | |
| SCHEMBL6183019 | 0.83 | FFAR1 (0.47) | FFAR1CA2PPARGPIM3PIM2 | |
| SCHEMBL5383045 | 0.83 | FFAR1 (0.41) | FFAR1CA2PPARGPIM3PIM2 | |
| SCHEMBL1128669 | 0.82 | FFAR1 (0.49) | FFAR1CA2PPARGPIM3PIM2 | |
| SCHEMBL5399580 | 0.82 | FFAR1 (0.61) | FFAR1PPARGMAOACISD1ALDH1A1 | |
| SCHEMBL5761010 | 0.82 | CA2 (0.49) | FFAR1CA2PPARGALDH1A1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458697-B1 | BIPHENYLMETHYL-THIAZOLIDINEDIONES AND ANALOGUES AND THEIR USE AS PPAR-GAMMA ACTIVATORS | GALDERMA RES & DEV (FR) | 2006-09-06 | — | — | EP | disclosed |