Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | F13A1 | P00488 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5390720 | 0.84 | FFAR1 (0.51) | FFAR1KMT2APPARGALDH1A1CYP2C9 | |
| SCHEMBL5397270 | 0.84 | FFAR1 (0.51) | FFAR1KMT2APPARGALDH1A1CYP2C9 | |
| SCHEMBL5383045 | 0.83 | FFAR1 (0.41) | FFAR1CA2PPARGTDP1LTB4R | |
| SCHEMBL1128669 | 0.74 | FFAR1 (0.49) | FFAR1CA2PPARGALDH1A1 | |
| SCHEMBL5392920 | 0.73 | FFAR1 (0.48) | FFAR1F13A1PPARGHPGDALDH1A1 | |
| SCHEMBL6986558 | 0.73 | FFAR1 (0.41) | FFAR1CA2PPARGTDP1 | |
| SCHEMBL6473789 | 0.72 | FFAR1 (0.58) | FFAR1PPARGALDH1A1L3MBTL1 | |
| SCHEMBL5760347 | 0.72 | FFAR1 (0.47) | FFAR1CA2PPARGALDH1A1 | |
| SCHEMBL5390713 | 0.71 | FFAR1 (0.52) | FFAR1PPARGCYP2C9 | |
| SCHEMBL5397263 | 0.71 | FFAR1 (0.52) | FFAR1PPARGCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294639-B2 | Biaromatic ligand activators of PPARγ receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-11-13 | — | — | US | disclosed |