Butyric Acid

Butyric Acid

SCHEMBL538385

CCC(=O)OC(C)Oc1ccccc1.CCCC(=O)O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.43
MTNR1A P48039 4/20 0.40
MTNR1B P49286 4/20 0.40
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
MAPT P10636 1/20 0.39
FFAR3 O14843 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
ELANE P08246 1/20 0.38
PPARG P37231 3/20 0.38
PPARA Q07869 3/20 0.38
TSHR P16473 2/20 0.37
ALDH1A1 P00352 1/20 0.36
CYP1A2 P05177 1/20 0.36
GAA P10253 1/20 0.36
CYP2C9 P11712 1/20 0.36
PKM P14618 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL974817 0.91 MTNR1A (0.46) MTNR1AMTNR1BMAPTELANEPPARG
SCHEMBL7753878 0.88 MTNR1A (0.44) FFAR1MTNR1AMTNR1BCES2CES1
SCHEMBL10535975 0.84 FFAR1 (0.47) FFAR1MTNR1AMTNR1BMAPTPPARG
Ethyl Propionate SCHEMBL1868755 0.84 LMNA (0.45) MTNR1AMTNR1BMAPTELANETSHR
SCHEMBL7576072 0.82 MTNR1A (0.47) FFAR1MTNR1AMTNR1BMAPTPPARG
SCHEMBL10063721 0.82 ESR1 (0.44) MTNR1AMTNR1BMAPTELANEPPARG
SCHEMBL29175524 0.81 LMNA (0.51) MTNR1AMTNR1BCES2CES1MAPT
SCHEMBL7492100 0.79 LMNA (0.54) CES2CES1MAPTTSHRALDH1A1
SCHEMBL14698120 0.79 LMNA (0.54) CES2CES1MAPTTSHRALDH1A1
SCHEMBL15988450 0.79 LMNA (0.54) CES2CES1MAPTTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9701177-B2 Ceramic coated automotive heat exchanger components HENKEL AG & CO. KGAA (DE) 2017-07-11 US disclosed
CN-102575916-A Ceramic-coated automotive heat exchanger element HENKEL AG & CO KGAA 2012-07-11 CN disclosed
EP-2414764-A2 CERAMIC COATED AUTOMOTIVE HEAT EXCHANGER COMPONENTS Henkel AG & Co. KGaA (DE) 2012-02-08 EP disclosed
US-20100252241-A1 CERAMIC COATED AUTOMOTIVE HEAT EXCHANGER COMPONENTS HENKEL AG & CO. KGAA (DE) 2010-10-07 US disclosed
WO-2010114988-A2 CERAMIC COATED AUTOMOTIVE HEAT EXCHANGER COMPONENTS HENKEL AG & CO. KGAA (DE) 2010-10-07 WO disclosed