Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 14/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5391604 | 0.84 | HDAC6 (0.67) | HDAC1HDAC8HDAC6HDAC11 | |
| SCHEMBL3813568 | 0.83 | TSHR (0.42) | HDAC1 | |
| SCHEMBL5696343 | 0.83 | HDAC1 (1.00) | HDAC1HDAC8HDAC6HDAC3HDAC11 | |
| SCHEMBL5381638 | 0.80 | HDAC6 (0.55) | HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL4611525 | 0.79 | HDAC6 (0.46) | HDAC1HDAC8HDAC6 | |
| SCHEMBL4657405 | 0.78 | HDAC1 (0.69) | HDAC1HDAC8HDAC6HDAC3HDAC11 | |
| SCHEMBL4654851 | 0.78 | HDAC1 (0.69) | HDAC1HDAC8HDAC6HDAC3HDAC11 | |
| SCHEMBL5391731 | 0.77 | HDAC6 (0.54) | HDAC1HDAC8HDAC6 | |
| SCHEMBL5417544 | 0.76 | PLK1 (0.56) | HDAC1HDAC8HDAC6HDAC3HDAC11 | |
| SCHEMBL6393053 | 0.76 | HDAC1 (0.51) | HDAC1HDAC8HDAC6HDAC3HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7282522-B2 | Hydroxamic acid derivatives and the method for preparing thereof | AMOREPACIFIC CORPORATION (KR) | 2007-10-16 | — | — | US | claimed |