Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GALR3 | O60755 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5381638 | 0.86 | HDAC6 (0.55) | PLK1HDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL6919330 | 0.85 | PLK1 (0.74) | PLK1HDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL3458378 | 0.84 | ALDH1A1 (0.47) | PLK1KDM4ETHRATHRBRARB | |
| SCHEMBL4658151 | 0.81 | HDAC1 (0.59) | PLK1HDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL4657440 | 0.81 | HDAC1 (0.59) | PLK1HDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL8060359 | 0.81 | HDAC1 (0.70) | PLK1HDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL9504756 | 0.79 | HDAC1 (0.73) | PLK1HDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL5391604 | 0.78 | HDAC6 (0.67) | HDAC1HDAC6HDAC2HDAC8KDM4E | |
| SCHEMBL10013045 | 0.78 | ESR1 (0.52) | TRPV1KDM4ETHRATHRB | |
| SCHEMBL5385421 | 0.77 | TRPV1 (0.76) | PLK1HDAC1HDAC6HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7282522-B2 | Hydroxamic acid derivatives and the method for preparing thereof | AMOREPACIFIC CORPORATION (KR) | 2007-10-16 | — | — | US | claimed |