Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5391604 | 0.84 | HDAC6 (0.67) | HDAC6HDAC1HDAC8ALDH1A1HDAC2 | |
| SCHEMBL5391731 | 0.83 | HDAC6 (0.54) | HDAC6HDAC1HDAC8SMN1; SMN2RAB9A | |
| SCHEMBL5384571 | 0.79 | HDAC1 (0.69) | HDAC6HDAC1HDAC8 | |
| SCHEMBL5381638 | 0.78 | HDAC6 (0.55) | HDAC6HDAC1HDAC8ALDH1A1HDAC2 | |
| SCHEMBL4656681 | 0.78 | HDAC6 (0.51) | HDAC6HDAC1HDAC8ALDH1A1MAPT | |
| SCHEMBL28869687 | 0.75 | HDAC6 (0.69) | HDAC6HDAC1HDAC8HDAC2SMN1; SMN2 | |
| SCHEMBL4655697 | 0.75 | HDAC6 (0.51) | HDAC6HDAC1HDAC8ALDH1A1MAPT | |
| SCHEMBL5417544 | 0.73 | PLK1 (0.56) | HDAC6HDAC1HDAC8HDAC2NPC1 | |
| SCHEMBL8076219 | 0.72 | BRD4 (0.37) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL6674162 | 0.68 | HDAC6 (0.89) | HDAC6HDAC1HDAC8ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660437-B1 | HYDROXAMIC ACID DERIVATIVES AND THE METHOD FOR PREPARING THEREOF | AMOREPACIFIC CORP (KR) | 2008-10-15 | — | — | EP | disclosed |