Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.58 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.58 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.58 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.58 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329089 | 1.00 | ALDH1A1 (0.62) | ALDH1A1KDM4EGAAMAPTKMT2A | |
| SCHEMBL5384610 | 1.00 | ALDH1A1 (0.62) | ALDH1A1KDM4EGAAMAPTKMT2A | |
| SCHEMBL25190699 | 0.89 | ALDH1A1 (0.51) | ALDH1A1KDM4EGAAMAPTKMT2A | |
| SCHEMBL10909091 | 0.81 | GRIN2D (0.68) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL22198126 | 0.81 | GRIN2D (0.68) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL4275683 | 0.80 | KMT2A (0.64) | ALDH1A1KDM4EGAAMAPTKMT2A | |
| SCHEMBL5668373 | 0.80 | KMT2A (0.64) | ALDH1A1KDM4EGAAMAPTKMT2A | |
| SCHEMBL27198359 | 0.80 | KMT2A (0.64) | ALDH1A1KDM4EGAAMAPTKMT2A | |
| SCHEMBL4275687 | 0.80 | KMT2A (0.64) | ALDH1A1KDM4EGAAMAPTKMT2A | |
| SCHEMBL9118994 | 0.79 | ALDH1A1 (0.63) | ALDH1A1KDM4EGAAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230346903-A1 | GROUP B STREPTOCOCCUS POLYSACCHARIDE-PROTEIN CONJUGATES, METHODS FOR PRODUCING CONJUGATES, IMMUNOGENIC COMPOSITIONS COMPRISING CONJUGATES, AND USES THEREOF | PFIZER INC. (US) | 2023-11-02 | — | — | US | disclosed |
| US-20230346903-A1 | GROUP B STREPTOCOCCUS POLYSACCHARIDE-PROTEIN CONJUGATES, METHODS FOR PRODUCING CONJUGATES, IMMUNOGENIC COMPOSITIONS COMPRISING CONJUGATES, AND USES THEREOF | PFIZER INC. (US) | 2023-11-02 | — | — | US | disclosed |
| US-20230346903-A1 | GROUP B STREPTOCOCCUS POLYSACCHARIDE-PROTEIN CONJUGATES, METHODS FOR PRODUCING CONJUGATES, IMMUNOGENIC COMPOSITIONS COMPRISING CONJUGATES, AND USES THEREOF | PFIZER INC. (US) | 2023-11-02 | — | — | US | disclosed |
| US-11147865-B2 | Immunogenic compositions and uses thereof | PFIZER INC. (US) | 2021-10-19 | — | — | US | disclosed |
| US-20210145957-A1 | GROUP B STREPTOCOCCUS POLYSACCHARIDE-PROTEIN CONJUGATES, METHODS FOR PRODUCING CONJUGATES, IMMUNOGENIC COMPOSITIONS COMPRISING CONJUGATES, AND USES THEREOF | PFIZER INC. (US) | 2021-05-20 | — | — | US | disclosed |
| US-10946086-B2 | Group B Streptococcus polysaccharide-protein conjugates, methods for producing conjugates, immunogenic compositions comprising conjugates, and uses thereof | PFIZER INC. (US) | 2021-03-16 | — | — | US | disclosed |
| US-10946086-B2 | Group B Streptococcus polysaccharide-protein conjugates, methods for producing conjugates, immunogenic compositions comprising conjugates, and uses thereof | PFIZER INC. (US) | 2021-03-16 | — | — | US | disclosed |
| US-20200368340-A1 | Immunogenic Compositions and Uses Thereof | PFIZER INC. | 2020-11-26 | — | — | US | disclosed |
| US-10751402-B2 | Immunogenic compositions and uses thereof | PFIZER INC. (US) | 2020-08-25 | — | — | US | disclosed |
| US-20190142922-A1 | GROUP B STREPTOCOCCUS POLYSACCHARIDE-PROTEIN CONJUGATES, METHODS FOR PRODUCING CONJUGATES, IMMUNOGENIC COMPOSITIONS COMPRISING CONJUGATES, AND USES THEREOF | PFIZER INC. | 2019-05-16 | — | — | US | disclosed |
| US-20110158907-A1 | DIPHENYL-HETEROARYL DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | THE TRUSTEES OF THE UNIVERISTY OF PENNSYLVANIA (US) | 2011-06-30 | — | — | US | disclosed |
| US-20110158907-A1 | DIPHENYL-HETEROARYL DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | THE TRUSTEES OF THE UNIVERISTY OF PENNSYLVANIA (US) | 2011-06-30 | — | — | US | disclosed |
| WO-2008131148-A1 | DIPHENYL-HETEROARYL DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2008-10-30 | — | — | WO | disclosed |
| US-7220768-B2 | Isoxazole-containing thiourea inhibitors useful for treatment of varicella zoster virus | WYETH HOLDINGS CORP. (US) | 2007-05-22 | — | — | US | disclosed |
| WO-2004072052-A2 | ISOXASOLE-CONTAINING THIOUREA INHIBITORS USEFUL FOR TREATMENT OF VARICELLA ZOSTER VIRUS | WYETH HOLDINGS CORPORATION (US) | 2004-08-26 | — | — | WO | disclosed |
| US-20040157900-A1 | Isoxazole-containing thiourea inhibitors useful for treatment of varicella zoster virus | WYETH HOLDINGS CORPORATION | 2004-08-12 | — | — | US | disclosed |
| US-4581365-A | Trichloroacryloyl oxime fungicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-04-08 | — | — | US | disclosed |
| US-4321369-A | INDOLE DYES | STERLING DRUG INC. (US) | 1982-03-23 | — | — | US | disclosed |
| EP-0035773-A2 | Substituted oximes, process for preparing them and duplicating and marking systems | STERLING DRUG INC. (US) | 1981-09-16 | — | — | EP | disclosed |
| US-4283077-A | PRESSURE SENSITIVE CARBONLESS DUPLICATING SYSTEMS AND THERMAL MARKING SYSTEMS | STERLING DRUG INC. (US) | 1981-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110158907-A1 | DIPHENYL-HETEROARYL DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | APP, APBA1, BACE2 | ALDH1A1 3983/4885KDM4E 4133/4885GAA 1299/4885 |
| US-20200368340-A1 | Immunogenic Compositions and Uses Thereof | FCGR3B, SIGLEC7, SIGLEC9 | ALDH1A1 4694/4885KDM4E 3728/4885GAA 842/4885 |
| US-20040157900-A1 | Isoxazole-containing thiourea inhibitors useful for treatment of varicella zoster virus | TPMT, TPX2, IRF3 | ALDH1A1 3213/4885KDM4E 438/4885GAA 2905/4885 |
| US-11147865-B2 | Immunogenic compositions and uses thereof | FCGR3B, SIGLEC7, SIGLEC9 | ALDH1A1 4694/4885KDM4E 3728/4885GAA 842/4885 |
| US-20190142922-A1 | GROUP B STREPTOCOCCUS POLYSACCHARIDE-PROTEIN CONJUGATES, METHODS FOR PRODUCING CONJUGATES, IMMUNOGENIC COMPOSITIONS COMPRISING CONJUGATES, AND USES THEREOF | SIGLEC7, SIGLEC9, FCGR3B | ALDH1A1 4380/4885KDM4E 2366/4885GAA 1285/4885 |
| US-10946086-B2 | Group B Streptococcus polysaccharide-protein conjugates, methods for producing conjugates, immunogenic compositions comprising conjugates, and uses thereof | SIGLEC7, SIGLEC9, FCGR3B | ALDH1A1 4380/4885KDM4E 2366/4885GAA 1285/4885 |
| US-10751402-B2 | Immunogenic compositions and uses thereof | FCGR3B, SIGLEC7, SIGLEC9 | ALDH1A1 4694/4885KDM4E 3728/4885GAA 842/4885 |
| US-20230346903-A1 | GROUP B STREPTOCOCCUS POLYSACCHARIDE-PROTEIN CONJUGATES, METHODS FOR PRODUCING CONJUGATES, IMMUNOGENIC COMPOSITIONS COMPRISING CONJUGATES, AND USES THEREOF | SIGLEC7, SIGLEC9, FCGR3B | ALDH1A1 4380/4885KDM4E 2366/4885GAA 1285/4885 |
| US-20210145957-A1 | GROUP B STREPTOCOCCUS POLYSACCHARIDE-PROTEIN CONJUGATES, METHODS FOR PRODUCING CONJUGATES, IMMUNOGENIC COMPOSITIONS COMPRISING CONJUGATES, AND USES THEREOF | SIGLEC7, SIGLEC9, FCGR3B | ALDH1A1 4369/4885KDM4E 2443/4885GAA 1179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.