Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FARS2 | O95363 | 5/20 | 0.56 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | ADCY2 | Q08462 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | EIF4E | P06730 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29941604 | 1.00 | FARS2 (0.56) | FARS2MDM2NPC1LMNAPKM | |
| SCHEMBL14592639 | 0.93 | FARS2 (0.66) | FARS2MDM2NPC1LMNAPKM | |
| SCHEMBL14592567 | 0.88 | FARS2 (0.56) | FARS2LMNAADCY2POLBEIF4E | |
| SCHEMBL13104371 | 0.71 | FARS2 (0.74) | FARS2NPC1LMNAPKMRAB9A | |
| SCHEMBL13104427 | 0.71 | FARS2 (0.74) | FARS2NPC1LMNAPKMRAB9A | |
| SCHEMBL14592624 | 0.67 | ADCY2 (0.56) | ADCY2 | |
| SCHEMBL13843264 | 0.64 | FARS2 (0.57) | FARS2NPC1LMNAPKMRAB9A | |
| SCHEMBL13104431 | 0.64 | FARS2 (0.57) | FARS2NPC1LMNAPKMRAB9A | |
| SCHEMBL13104394 | 0.63 | FARS2 (0.64) | FARS2NPC1PKMRAB9AGAA | |
| SCHEMBL13398813 | 0.63 | NPSR1 (0.51) | LMNAADCY2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7167801-B2 | Method of identifying potential inhibitors of human papillomavirus protein E2 using x-ray atomic coordinates | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2007-01-23 | — | — | US | disclosed |
| US-7167801-B2 | Method of identifying potential inhibitors of human papillomavirus protein E2 using x-ray atomic coordinates | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2007-01-23 | — | — | US | disclosed |