SCHEMBL538529

SCHEMBL538529

O=C1OC(=O)c2cc1ccc2C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.50
HNF4A P41235 2/20 0.43
ACMSD Q8TDX5 2/20 0.43
CA12 O43570 3/20 0.41
CA7 P43166 3/20 0.41
CA1 P00915 2/20 0.41
CA4 P22748 1/20 0.41
PTPN1 P18031 1/20 0.41
DHFR P00374 1/20 0.39
MCL1 Q07820 1/20 0.39
HSD17B10 Q99714 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
DCLRE1A Q6PJP8 1/20 0.39
DCLRE1B Q9H816 1/20 0.39
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
KDM4E B2RXH2 1/20 0.38
GFER P55789 1/20 0.38
KMT2A Q03164 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL168301 0.94 TYMS (0.51) TYMSHNF4AACMSDCA12CA7
SCHEMBL2188108 0.93 TYMS (0.49) TYMSHNF4AACMSDCA12CA7
SCHEMBL11863723 0.90 TYMS (0.45) TYMSHNF4AACMSDCA12CA7
SCHEMBL18352945 0.83 CHEK1 (0.40) TYMSCA12PTPN1SMN1; SMN2CA9
SCHEMBL11863110 0.82 TYMS (0.42) TYMSHNF4AACMSDCA12CA7
SCHEMBL14321815 0.82 TYMS (0.49) TYMSHNF4AACMSDCA12CA7
SCHEMBL18356468 0.81 TYMS (0.37) TYMSCA12CA7CA1CA4
SCHEMBL475851 0.81 ACMSD (0.44) TYMSACMSDCA12CA7CA1
SCHEMBL1142632 0.80 TYMS (0.50) TYMSHNF4AACMSDCA12CA7
SCHEMBL11867738 0.80 TYMS (0.43) TYMSHNF4AACMSDCA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024141320-A1 RADIATION CURABLE LIQUID COMPOSITION, PROCESS OF FORMING 3D-PRINTED OBJECT AND 3D-PRINTED OBJECT BASF SE (DE) 2024-07-04 WO claimed
WO-2024141321-A1 PHOTOCURABLE HYPERBRANCHED POLYIMIDE AND PREPARATION PROCESS THEREOF BASF SE (DE) 2024-07-04 WO claimed
EP-3921382-A1 DEGRADABLE URETHANE AND URETHANE-UREA SYSTEMS LANXESS Corporation (US) 2021-12-15 EP claimed
WO-2020163674-A1 DEGRADABLE URETHANE AND URETHANE-UREA SYSTEMS LANXESS SOLUTIONS US INC. (US) 2020-08-13 WO claimed
CN-106268956-B A kind of double-core carboxyl cobalt phthalocyanine/attapulgite composite photo-catalyst and preparation method thereof 常州大学 2019-05-14 CN claimed
EP-3464446-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2019-04-10 EP claimed
EP-3350250-A1 POLYMER GELS, METHOD OF PREPARATION AND USES THEREOF Rhodia Acetow GmbH (DE) 2018-07-25 EP claimed
WO-2018019961-A1 IMPROVED IMMUNOFIXATION ELECTROPHORESIS METHOD WITH TARGET COMPONENT ON-GEL IMMUNODISPLACEMENT SEBIA (FR) 2018-02-01 WO claimed
WO-2017202698-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2017-11-30 WO claimed
WO-2017045994-A1 POLYMER GELS, METHOD OF PREPARATION AND USES THEREOF SOLVAY ACETOW GMBH (DE) 2017-03-23 WO claimed
WO-2005056639-A1 POLYMERIC DISPERSANTS AND DISPERSIONS CONTAINING SAME SUN CHEMICAL CORPORATION (US) 2005-06-23 WO claimed
WO-2005012390-A1 SULFONATED ALIPHATIC-AROMATIC COPOLYESTERS AND SHAPED ARTICLES PRODUCED THEREFROM E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-02-10 WO claimed
WO-2005003209-A1 ALIPHATIC-AROMATIC POLYESTHERESTER COMPOSITIONS, ARTICLES, FILMS, COATING AND LAMINATES AND PROCESSES FOR PRODUCING SAME E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-01-13 WO claimed
WO-2005000940-A1 SULFONATED ALIPHATIC-AROMATIC COPOLYESTERS AND SHAPED ARTICLES PRODUCED THEREFROM E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-01-06 WO claimed
WO-2004111092-A1 MODIFIED ALGINIC ACID OR ALGINIC ACID DERIVATIVES AND THERMOSETTING ANTI-REFLECTIVE COMPOSITIONS THEREOF AZ ELECTRONIC MATERIALS USA CORP. (US) 2004-12-23 WO claimed
WO-2004035284-A1 PROCESSES FOR PRODUCING VERY LOW IV POLYESTER RESIN E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-04-29 WO claimed
CN-1073544-C Method for recovering liquid-phase phthalic anhydride by using rectifying tower EXXON MOBILE CHEMICAL PATENTS (US) 2001-10-24 CN claimed
WO-1998016937-A1 ELECTRICAL INSULATION USING LIQUID CRYSTAL THERMOSET EPOXY RESINS SIEMENS WESTINGHOUSE POWER CORPORATION (US) 1998-04-23 WO claimed
CN-1150417-A Method for recovering liquid-phase phthalic anhydride by using rectifying tower EXXON CHEMICAL PATENTS INC (US) 1997-05-21 CN claimed
CN-1069745-A dispersant for carbon black-filled foam CELOTEX CORP (US) 1993-03-10 CN claimed