Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12132658 | 0.87 | CES1 (0.44) | CES1THRBTSHRMEN1KMT2A | |
| SCHEMBL14706846 | 0.85 | THRB (0.47) | THRBMEN1KMT2APOLB | |
| SCHEMBL11152951 | 0.85 | CES1 (0.53) | CES1THRBTSHRMEN1KMT2A | |
| SCHEMBL15412040 | 0.85 | CES1 (0.53) | CES1THRBTSHRMEN1KMT2A | |
| SCHEMBL15412436 | 0.85 | CES1 (0.53) | CES1THRBTSHRMEN1KMT2A | |
| SCHEMBL4879022 | 0.85 | CES1 (0.53) | CES1THRBTSHRMEN1KMT2A | |
| SCHEMBL13165932 | 0.85 | CES1 (0.53) | CES1THRBTSHRMEN1KMT2A | |
| SCHEMBL160932 | 0.83 | THRB (0.46) | THRBMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL30492030 | 0.82 | CYP3A4 (0.42) | THRBTSHRLPAR1LPAR3LPAR2 | |
| SCHEMBL2340995 | 0.81 | MEN1 (0.48) | CES1THRBTSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265236-B2 | Polypodal silanes with embedded hydrophilicity | GELEST, INC. (US) | 2007-09-04 | — | — | US | disclosed |
| US-20050187400-A1 | Polypodal silanes with embedded hydrophilicity | GELEST, INC. | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187400-A1 | Polypodal silanes with embedded hydrophilicity | SDC2, PCNA, PDS5B | CES1 3709/4885THRB 4575/4885TSHR 4796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.