SCHEMBL538609

SCHEMBL538609

Cc1ccc(-c2ccccc2-c2ccc(N)cc2-c2ccc(C)c(C)c2)cc1C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
PLA2G7 Q13093 1/20 0.50
NPC1 O15118 4/20 0.47
RAB9A P51151 4/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
PTPRC P08575 2/20 0.47
NPSR1 Q6W5P4 2/20 0.47
LMNA P02545 2/20 0.47
APAF1 O14727 1/20 0.47
TDP2 O95551 1/20 0.47
NSD2 O96028 1/20 0.47
PLA2G1B P04054 1/20 0.47
POLB P06746 1/20 0.47
CTSL P07711 1/20 0.47
HPGD P15428 1/20 0.47
ALOX12 P18054 1/20 0.47
PLCG1 P19174 1/20 0.47
CTSS P25774 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5414111 0.91 ALDH1A1 (0.50) ALDH1A1PLA2G7NPC1RAB9ASMN1; SMN2
SCHEMBL5414116 0.87 ALDH1A1 (0.52) ALDH1A1PLA2G7NPC1MEN1KMT2A
SCHEMBL28022262 0.81 ESR2 (0.49) ALDH1A1PLA2G7NPC1RAB9ASMN1; SMN2
SCHEMBL7728888 0.80 HTR7 (0.43) ALDH1A1PLA2G7NPC1RAB9ASMN1; SMN2
SCHEMBL6011290 0.79 ALDH1A1 (0.58) ALDH1A1PLA2G7NPC1RAB9ASMN1; SMN2
SCHEMBL31601446 0.79 ALDH1A1 (0.52) ALDH1A1PLA2G7NPC1RAB9ASMN1; SMN2
SCHEMBL55384 0.79 PTPRC (0.52) ALDH1A1PLA2G7NPC1RAB9ASMN1; SMN2
Hydrochloric Acid SCHEMBL6571955 0.78 ALDH1A1 (0.56) ALDH1A1PLA2G7NPC1RAB9ASMN1; SMN2
SCHEMBL5685052 0.78 TSHR (0.61) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL396194 0.77 ALDH1A1 (0.52) ALDH1A1PLA2G7NPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10212267-A None JP disclosed
JP-10212268-A None JP disclosed
US-8173343-B2 Electrophotographic photoconductor, image forming apparatus using the same, and process cartridge RICOH COMPANY, LTD. (JP) 2012-05-08 US disclosed
EP-2146251-B1 Electrophotographic photoconductor, image forming apparatus using the same, and process cartridge RICOH CO LTD (JP) 2012-02-08 EP disclosed
US-20100015538-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING APPARATUS USING THE SAME, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2010-01-21 US disclosed
EP-2146251-A1 Electrophotographic photoconductor, image forming apparatus using the same, and process cartridge Ricoh Company, Ltd. (JP) 2010-01-20 EP disclosed
US-5902901-A Arylamine processes XEROX CORPORATION (US) 1999-05-11 US disclosed
JP-H10212267-A PROCESS FOR PREPARING ARYLAMINE XEROX CORP 1998-08-11 JP disclosed
JP-H10212268-A PROCESS FOR PREPARING ARYLAMINE XEROX CORP 1998-08-11 JP disclosed
EP-0856508-A1 Processes for the preparation of arylamines XEROX CORPORATION (US) 1998-08-05 EP disclosed
US-5723669-A Arylamine processes XEROX CORPORATION (US) 1998-03-03 US disclosed
US-5723671-A Arylamine processes XEROX CORPORATION (US) 1998-03-03 US disclosed
US-5705697-A ULLMAN CONDENSATION OF IODOXYLENE WITH N-(3,4-DIMETHYLPHENYL)-4-BIPHENYLAMINE CATALYZED BY COPPER/I/ COMPLEXED TO NITROGEN-CONTAINING HETEROARYL LIGAND XEROX CORPORATION (US) 1998-01-06 US disclosed