SCHEMBL5386141

SCHEMBL5386141

Cc1c(F)cc(Cl)c(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22399221 0.84 HDAC1 (0.35) HDAC1HDAC6POLBAPEX1
SCHEMBL16589257 0.79 POLB (0.33) HDAC1HDAC6POLBAPEX1
SCHEMBL18885784 0.76 HDAC1 (0.32) HDAC1HDAC6POLBAPEX1
SCHEMBL25787063 0.75 HDAC1 (0.31) HDAC1HDAC6
SCHEMBL22399184 0.75 PTGS2 (0.33) HDAC1HDAC6
SCHEMBL22824394 0.75 PTGS2 (0.36)
SCHEMBL22989874 0.75 CYP3A4 (0.35) HDAC1HDAC6
SCHEMBL172019 0.75 CA1 (0.35) HDAC1HDAC6
SCHEMBL1042005 0.75 KDM1A (0.32)
SCHEMBL10144167 0.75 TSHR (0.41) HDAC1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120157560-A Preparation method of p-chlorotrifluorotoluene 山东道可化学有限公司 2025-06-17 CN claimed
CN-120015405-A Dustless drag chain cable 无锡胜维电气有限公司 2025-05-16 CN claimed
CN-119161255-A Production process of 2, 6-dichloro-4-trifluoromethyl aniline 湖北丰山新材料科技有限公司 2024-12-20 CN claimed
CN-118563333-A Composition for cleaning metal parts 胜牌全球产品知识产权有限公司 2024-08-30 CN claimed
CN-118563334-A Composition for cleaning metal parts 胜牌全球产品知识产权有限公司 2024-08-30 CN claimed
CN-221536655-U Para-chlorotrifluoro Chlorination kettle for toluene production 内蒙古大中实业化工有限公司 2024-08-16 CN claimed
CN-221536493-U Cleaning equipment of stirring mechanism for chlorotrifluorotoluene production 内蒙古大中实业化工有限公司 2024-08-16 CN claimed
CN-118126628-B Multifunctional rubber-plastic protective agent for vehicle and preparation method and application thereof 广州市标榜汽车用品实业有限公司 2024-07-12 CN claimed
CN-118271176-A Preparation method of 4-chloro-3, 5-dinitrobenzotrifluoride 江西巍华化学有限公司 2024-07-02 CN claimed
CN-115611717-B Preparation method of polyfluorobenzaldehyde 上海万溯药业有限公司 2024-06-28 CN claimed
CN-113563197-B Method for preparing 3-nitro-4-chlorotrifluorotoluene by continuous adiabatic nitration and micro-reaction equipment 山东道可化学有限公司 2023-10-10 CN claimed
CN-219765306-U Fluorination device for producing chlorotrifluorotoluene 山东道可化学有限公司 2023-09-29 CN claimed
CN-116622574-A Halotoluene degrading bacteria, microbial inoculum and application thereof 南京农业大学 2023-08-22 CN claimed
CN-115999481-B Continuous production method of p-chlorobenzoyl chloride 山东道可化学有限公司 2023-07-18 CN claimed
CN-106892792-B Continuous synthesis method and equipment of 3, 4-dichloro benzotrifluoride 山东道可化学有限公司 2023-05-23 CN claimed
CN-115999481-A Continuous production method of p-chlorobenzoyl chloride 山东道可化学有限公司 2023-04-25 CN claimed
CN-216538482-U Chlorination cauldron is used in production of p-chloro benzotrifluoride 山东道可化学有限公司 2022-05-17 CN claimed
CN-112867713-A Process for preparing imidazole derivatives 拜耳公司 2021-05-28 CN claimed
CN-106810423-B Preparation method of pentafluorophenol 上海万溯药业有限公司 2020-07-07 CN claimed
EP-1171302-B1 METHOD AND COMPOSITION FOR COSMETICALLY REPAIRING A BLEMISH IN A POLYOLEFIN OBJECT STEVENSON MICHAEL J (US) 2004-06-30 EP claimed