Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528070 | 0.83 | CYP3A4 (0.41) | ALDH1A1 | |
| SCHEMBL7939692 | 0.80 | — | — | |
| SCHEMBL1756490 | 0.79 | CYP3A4 (0.40) | KDM1AKDM1BCES2CES1ALDH1A1 | |
| SCHEMBL11192387 | 0.79 | GRIN2D (0.39) | KDM1AKDM1BALDH1A1TDP1 | |
| SCHEMBL41646 | 0.75 | CA1 (0.43) | CES2CES1ALDH1A1 | |
| SCHEMBL7702552 | 0.75 | CA1 (0.43) | CES2CES1ALDH1A1 | |
| SCHEMBL24610552 | 0.75 | POLB (0.35) | — | |
| SCHEMBL18167032 | 0.75 | — | — | |
| SCHEMBL5386141 | 0.75 | HDAC1 (0.35) | — | |
| SCHEMBL8571604 | 0.75 | HSD17B10 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362860-B1 | Method for producing tetrakis (fluoraryl)borate magnesium compound | NIPPON CATALYTIC CHEM IND (JP) | 2010-09-15 | — | — | EP | claimed |
| US-7205441-B2 | Method for producing tetrakis (fluoroaryl) borate-magnesium compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2007-04-17 | — | — | US | claimed |
| US-20030216598-A1 | Method for producing tetrakis ( fluoroaryl) borate-magnesium compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2003-11-20 | — | — | US | claimed |
| EP-1362860-A1 | Method for producing tetrakis (fluoroaryl) borate magnesium compound | Nippon Shokubai Co., Ltd. (JP) | 2003-11-19 | — | — | EP | claimed |
| US-20230265055-A1 | STAT INIHIBITORY COMPOUNDS AND COMPOSITIONS | OXFORD FINANCE LLC | 2023-08-24 | — | — | US | disclosed |
| WO-2022051639-A1 | STAT INHIBITORY COMPOUNDS AND COMPOSITIONS | JANPIX LIMITED (US) | 2022-03-10 | — | — | WO | disclosed |
| CN-112368255-A | Preparation method of halogenated polyfluorobenzene | 谢尔盖·米哈伊洛维奇·伊古诺夫 | 2021-02-12 | — | — | CN | disclosed |
| EP-1955990-B1 | PROCESS FOR PRODUCTION OF BIPHENYL DERIVATIVES | TORAY FINECHEMICALS CO LTD (JP) | 2012-08-22 | — | — | EP | disclosed |
| CN-101296889-B | Process for production of biphenyl derivatives | TORAY FINECHEMICALS CO LTD | 2012-07-18 | — | — | CN | disclosed |
| CN-102531831-A | Preparation method for 1-chlorin-2,3,4,5-phenyl tetrafluoride | SHANGHAI SINOFLUORO SCIENT CO | 2012-07-04 | — | — | CN | disclosed |
| US-7943257-B2 | Electrolyte solvent and rechargeable lithium battery | SAMSUNG SDI CO., LTD. (KR) | 2011-05-17 | — | — | US | disclosed |
| US-7915455-B2 | Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-03-29 | — | — | US | disclosed |
| US-4321339-A | Fluorinated phenoxypropyl vinyl ether polymer | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-03-23 | — | — | US | disclosed |
| EP-0001825-B1 | METHOD OF PREPARING 2,4-DIFLUOROANILINE | MERCK & CO. INC. (US) | 1982-01-13 | — | — | EP | disclosed |
| US-4294988-A | Method of preparing 2,4-difluoroaniline | MERCK & CO., INC. (US) | 1981-10-13 | — | — | US | disclosed |
| US-4288574-A | POST HYDROXYLATION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-09-08 | — | — | US | disclosed |
| EP-0028161-A1 | Fluorinated phenolic polymer and process for its preparation | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-05-06 | — | — | EP | disclosed |
| EP-0001825-A1 | Method of preparing 2,4-difluoroaniline | MERCK & CO. INC. (US) | 1979-05-16 | — | — | EP | disclosed |
| US-4140719-A | Solid-liquid phase transfer catalysis improved method of preparing 2,4-difluoroaniline | MERCK & CO., INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4065259-A | ONE STEP, SYNTHETIC POLYMERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216598-A1 | Method for producing tetrakis ( fluoroaryl) borate-magnesium compound | KRAS, MGAM, CA3 | KDM1A 4098/4885KDM1B 3691/4885CES2 3957/4885 |
| US-20230265055-A1 | STAT INIHIBITORY COMPOUNDS AND COMPOSITIONS | STAT5B, STAT5A, STAT3 | KDM1A 3048/4885KDM1B 2123/4885CES2 4732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.