Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2556244 | 0.92 | HCAR2 (0.50) | HCAR2THRBLMNAALDH1A1TSHR | |
| SCHEMBL9555004 | 0.89 | HCAR2 (0.44) | HCAR2THRBLMNAALDH1A1TSHR | |
| SCHEMBL9419668 | 0.86 | TSHR (0.47) | HCAR2THRBLMNAALDH1A1TSHR | |
| SCHEMBL16125662 | 0.86 | HCAR2 (0.46) | HCAR2THRBLMNAALDH1A1TSHR | |
| SCHEMBL12268165 | 0.86 | HCAR2 (0.46) | HCAR2THRBLMNAALDH1A1TSHR | |
| SCHEMBL17791314 | 0.86 | THRB (0.51) | HCAR2THRBLMNAALDH1A1TSHR | |
| SCHEMBL12367978 | 0.86 | HCAR2 (0.46) | HCAR2THRBLMNAALDH1A1TSHR | |
| SCHEMBL4578050 | 0.86 | MEN1 (0.55) | HCAR2THRBLMNAALDH1A1TSHR | |
| SCHEMBL19270357 | 0.83 | MMP1 (0.45) | HCAR2LMNAMEN1KMT2ATGM2 | |
| SCHEMBL13052581 | 0.83 | CYP3A4 (0.44) | HCAR2THRBLMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273911-B2 | Self-adhesive addition-crosslinking silicone compositions | WACKER CHEMIE AG (DE) | 2007-09-25 | — | — | US | disclosed |
| EP-1510553-B1 | Self adhesive addtion-curable polysiloxane compositions. | WACKER CHEMIE AG (DE) | 2006-11-08 | — | — | EP | disclosed |
| US-7119159-B2 | Self-adhesive addition-crosslinking silicon compositions | WACKER-CHEMIE GMBH (DE) | 2006-10-10 | — | — | US | disclosed |
| EP-1510553-A1 | Self adhesive addtion-curable polysiloxane compositions. | Wacker-Chemie GmbH (DE) | 2005-03-02 | — | — | EP | disclosed |
| US-20050042462-A1 | Self-adhesive addition-crosslinking silicone compositions | WACKER-CHEMIE GMBH (DE) | 2005-02-24 | — | — | US | disclosed |
| EP-1375622-B1 | Self-adhesive addition curable silicone compositions | WACKER CHEMIE GMBH (DE) | 2004-09-15 | — | — | EP | disclosed |
| US-6790533-B2 | BLEND OF POLYSILOXANE AND FILLER | WACKER-CHEMIE GMBH (DE) | 2004-09-14 | — | — | US | disclosed |
| EP-1266948-B1 | Self adhesive heat curable 1-component silicone compositions | WACKER CHEMIE GMBH (DE) | 2004-07-14 | — | — | EP | disclosed |
| EP-1106662-B1 | Self-adhesive addition curable silicone elastomer compositions | WACKER CHEMIE GMBH (DE) | 2004-01-28 | — | — | EP | disclosed |
| EP-1375622-A1 | Self-adhesive addition curable silicone compositions | Wacker-Chemie GmbH (DE) | 2004-01-02 | — | — | EP | disclosed |
| US-20030236380-A1 | Self-adhesive addition-crosslinking silicon compositions | WACKER-CHEMIE GMBH (DE) | 2003-12-25 | — | — | US | disclosed |
| EP-1266948-A2 | Self adhesive heat curable 1-component silicone compositions | Wacker-Chemie GmbH (DE) | 2002-12-18 | — | — | EP | disclosed |
| US-20020187358-A1 | Self-adhesive thermally crosslinkable 1-component silicone compositions | WACKER-CHEMIE GMBH (DE) | 2002-12-12 | — | — | US | disclosed |