Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3946203 | 0.89 | TSHR (0.33) | TSHR | |
| SCHEMBL5396044 | 0.88 | TSHR (0.33) | TSHR | |
| SCHEMBL5399382 | 0.88 | ADA (0.33) | TSHR | |
| SCHEMBL14370814 | 0.85 | ADA (0.39) | TSHR | |
| SCHEMBL5386556 | 0.84 | ADORA2A (0.35) | ADORA2A | |
| SCHEMBL5390248 | 0.84 | ADORA2A (0.36) | CSNK2A1TSHRADORA2A | |
| SCHEMBL5399189 | 0.83 | TSHR (0.32) | TSHRHTR2AHTR2CHTR2B | |
| Bromide SCHEMBL5386504 | 0.82 | ADORA2A (0.36) | CSNK2A1TSHRADORA2A | |
| SCHEMBL5407292 | 0.82 | THRB (0.32) | TSHR | |
| SCHEMBL5391855 | 0.81 | LMNA (0.38) | CSNK2A1TSHRHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7285136-B2 | Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres | L'OREAL, SA (FR) | 2007-10-23 | — | — | US | disclosed |
| US-7285136-B2 | Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres | L'OREAL, SA (FR) | 2007-10-23 | — | — | US | disclosed |
| US-7285136-B2 | Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres | L'OREAL, SA (FR) | 2007-10-23 | — | — | US | disclosed |