Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.38 |
| ▸ | CYP21A2 | P08686 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5387223 | 1.00 | PTGS1 (0.39) | PTGS1PTGS2CYP17A1CYP21A2CYP11B1 | |
| SCHEMBL6982736 | 0.84 | PTGS1 (0.52) | PTGS1PTGS2CYP17A1CYP21A2CYP11B1 | |
| SCHEMBL16960755 | 0.84 | APP (0.41) | APPCNR2LMNATP53CYP3A4 | |
| SCHEMBL15145957 | 0.84 | APP (0.41) | APPCNR2LMNATP53CYP3A4 | |
| SCHEMBL27827613 | 0.82 | PTGS1 (0.33) | PTGS1PTGS2CYP17A1CYP21A2CYP11B1 | |
| SCHEMBL16974768 | 0.78 | PTGS1 (0.36) | PTGS1PTGS2CYP17A1CYP21A2CYP11B1 | |
| SCHEMBL16956200 | 0.76 | APP (0.36) | APPCNR2LMNATP53CYP3A4 | |
| SCHEMBL16962236 | 0.76 | PTGS1 (0.45) | PTGS1PTGS2CYP17A1CYP21A2CYP11B1 | |
| SCHEMBL18345588 | 0.75 | ALDH1A1 (0.39) | PTGS1PTGS2CYP17A1CYP21A2CYP11B1 | |
| SCHEMBL8956931 | 0.75 | CYP17A1 (0.36) | PTGS1PTGS2CYP17A1CYP21A2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297378-B2 | Fluorinated fused aromatics and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2007-11-20 | — | — | US | disclosed |
| US-20050258397-A1 | Fluorinated fused aromatics and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050258397-A1 | Fluorinated fused aromatics and their use in liquid-crystal mixtures | AFF1, AFF2, AFF4 | PTGS1 4356/4885PTGS2 4685/4885CYP17A1 796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.