Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10025891 | 0.81 | CYP3A4 (0.58) | CYP3A4ALDH1A1SMN1; SMN2ACHEPOLB | |
| SCHEMBL5383789 | 0.80 | DHFR (0.50) | CYP3A4ALDH1A1SMN1; SMN2POLBMEN1 | |
| SCHEMBL7710239 | 0.79 | CYP3A4 (0.58) | CYP3A4ALDH1A1SMN1; SMN2ACHEPOLB | |
| SCHEMBL5233561 | 0.79 | CYP3A4 (0.57) | CYP3A4ALDH1A1SMN1; SMN2ACHEPOLB | |
| SCHEMBL4043528 | 0.79 | ALDH1A1 (0.57) | CYP3A4ALDH1A1SMN1; SMN2ACHEPOLB | |
| SCHEMBL14337774 | 0.79 | CYP3A4 (0.57) | CYP3A4ALDH1A1SMN1; SMN2ACHEPOLB | |
| SCHEMBL8144226 | 0.79 | CYP3A4 (0.57) | CYP3A4ALDH1A1SMN1; SMN2ACHEPOLB | |
| SCHEMBL5381403 | 0.78 | CYP3A4 (0.48) | CYP3A4ALDH1A1SMN1; SMN2POLBMEN1 | |
| SCHEMBL12781853 | 0.77 | CYP3A4 (0.54) | CYP3A4ALDH1A1SMN1; SMN2ACHEPOLB | |
| SCHEMBL12118415 | 0.77 | CYP3A4 (0.54) | CYP3A4ALDH1A1SMN1; SMN2ACHEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62084077-A | — | — | None | — | — | JP | disclosed |
| US-12084456-B2 | Isocarbostyril alkaloids and functionalization thereof | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2024-09-10 | — | — | US | disclosed |
| US-20220064176-A1 | ISOCARBOSTYRIL ALKALOIDS AND FUNCTIONALIZATION THEREOF | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2022-03-03 | — | — | US | disclosed |
| WO-2020117894-A1 | ISOCARBOSTYRIL ALKALOIDS AND FUNCTIONALIZATION THEREOF | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2020-06-11 | — | — | WO | disclosed |
| EP-3640249-A1 | 4-AMINO-6-(HETEROCYCLIC)PICOLINATES AND 6-AMINO-2-(HETEROCYCLIC)PYRIMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2020-04-22 | — | — | EP | disclosed |
| CN-110583663-A | Compounds of formula (I) and their use as herbicides | 美国陶氏益农公司 | 2019-12-20 | — | — | CN | disclosed |
| US-9149038-B2 | 4-amino-6-(heterocyclic)picolinates and 6-amino-2-(heterocyclic)pyrimidine-4-carboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2015-10-06 | — | — | US | disclosed |
| US-20140274701-A1 | 4-AMINO-6-(HETEROCYCLIC)PICOLINATES AND 6-AMINO-2-(HETEROCYCLIC)PYRIMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2014-09-18 | — | — | US | disclosed |
| US-7312347-B2 | Substituted optically active disphosphine compound | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-12-25 | — | — | US | disclosed |
| US-7312347-B2 | Substituted optically active disphosphine compound | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-12-25 | — | — | US | disclosed |
| US-6545150-B2 | Preparing 1,1-dioxo-2-phenyl-3-carboxy-4-phenyl-1,2-benzo(e)-thiazines by a five-step process starting with a (2-(methyl-oxycarbonyl-)phenyl-sulfonamido-)benzene; alkylation; cyclization; hydroxylation; esterification and coupling | WARNER-LAMBERT COMPANY | 2003-04-08 | — | — | US | disclosed |
| US-6440962-B2 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS | WARNER-LAMBERT COMPANY | 2002-08-27 | — | — | US | disclosed |
| US-20020094980-A1 | Certain benzothiazine dioxide endothelin antagonists and processes for their preparation | BUNKER AMY MAE (US) | 2002-07-18 | — | — | US | disclosed |
| US-20010036944-A1 | Certain benzothiazine dioxide endothelin antagonists and processes for their preparation | BUNKER AMY MAE (US) | 2001-11-01 | — | — | US | disclosed |
| US-6265399-B1 | ALKYLATION; CYCLIZATION | WARNER-LAMBERT COMPANY | 2001-07-24 | — | — | US | disclosed |
| US-6252070-B1 | REACTING ARYL BROMIDE WITH BUTYLLITHIUM AND ZINC BROMIDE TO GIVE ARYL ZINC BROMIDE; REACTING WITH CORRESPONDING BENZOTHIAZINE COMPOUND | WARNER-LAMBERT COMPANY | 2001-06-26 | — | — | US | disclosed |
| EP-1009743-A1 | CERTAIN BENZOTHIAZINE DIOXIDE ENDOTHELIN ANTAGONISTS AND PROCESSES FOR THEIR PREPARATION | WARNER-LAMBERT COMPANY (US) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999012916-A1 | CERTAIN BENZOTHIAZINE DIOXIDE ENDOTHELIN ANTAGONISTS AND PROCESSES FOR THEIR PREPARATION | WARNER-LAMBERT COMPANY (US) | 1999-03-18 | — | — | WO | disclosed |
| US-5003091-A | Preparation of 3-memory-4,5-methylenedioxybenzaldehyde | RHONE-POULENC CHIMIE (FR) | 1991-03-26 | — | — | US | disclosed |
| JP-S6284077-A | PRODUCTION OF BENZYL ALCOHOL COMPOUND | MITSUBISHI CHEM IND LTD | 1987-04-17 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220064176-A1 | ISOCARBOSTYRIL ALKALOIDS AND FUNCTIONALIZATION THEREOF | NISCH, CIAPIN1, CA7 | CYP3A4 1056/4885ALDH1A1 1509/4885SMN1; SMN2 1380/4885 |
| US-12084456-B2 | Isocarbostyril alkaloids and functionalization thereof | NISCH, CIAPIN1, CA7 | CYP3A4 1056/4885ALDH1A1 1509/4885SMN1; SMN2 1380/4885 |
| US-20020094980-A1 | Certain benzothiazine dioxide endothelin antagonists and processes for their preparation | ECE1, EDNRA, EDNRB | CYP3A4 2670/4885ALDH1A1 1806/4885SMN1; SMN2 1432/4885 |
| US-20010036944-A1 | Certain benzothiazine dioxide endothelin antagonists and processes for their preparation | ECE1, EDNRA, EDNRB | CYP3A4 2670/4885ALDH1A1 1806/4885SMN1; SMN2 1432/4885 |
| US-20140274701-A1 | 4-AMINO-6-(HETEROCYCLIC)PICOLINATES AND 6-AMINO-2-(HETEROCYCLIC)PYRIMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, ABAT, PAH | CYP3A4 262/4885ALDH1A1 1287/4885SMN1; SMN2 4320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.