Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27795023 | 0.98 | DNM1 (0.48) | DNM1SPHK1HTTOPRM1USP2 | |
| SCHEMBL27578847 | 0.98 | DNM1 (0.48) | DNM1SPHK1HTTOPRM1USP2 | |
| SCHEMBL9765642 | 0.93 | SPHK1 (0.39) | DNM1SPHK1HTTOPRM1ALDH1A1 | |
| SCHEMBL4395975 | 0.79 | HTT (0.46) | DNM1SPHK1HTTUSP2ALDH1A1 | |
| SCHEMBL11444946 | 0.78 | SPHK1 (0.47) | DNM1SPHK1HTTOPRM1USP2 | |
| SCHEMBL136729 | 0.78 | DNM1 (0.50) | DNM1SPHK1HTTOPRM1 | |
| SCHEMBL16553558 | 0.78 | DNM1 (0.50) | DNM1SPHK1HTTOPRM1 | |
| SCHEMBL9730272 | 0.77 | DNM1 (0.43) | DNM1SPHK1HTTUSP2ALDH1A1 | |
| SCHEMBL10379772 | 0.77 | DNM1 (0.43) | DNM1SPHK1HTTUSP2ALDH1A1 | |
| SCHEMBL9273623 | 0.77 | DNM1 (0.48) | DNM1SPHK1HTTOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029155-A2 | AN IMPROVED PROCESS FOR PREPARATION OF PURE CELIPROLOL BASE | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |
| EP-0741705-A1 | 4-(2-(3-ARYLOXY-2-HYDROXYPROPYLAMINO ALKYLOXY)-5-NITROPHENYL)-1,4-DIHYDROPYRIDINES AS ANTIHYPERTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |
| EP-0522176-A1 | DIHYDROPYRIDINE COMPOUNDS, AND PROCESS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-01-13 | — | — | EP | disclosed |
| WO-1992013839-A1 | DIHYDROPYRIDINE COMPOUNDS, AND PROCESS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-20 | — | — | WO | disclosed |
| EP-0194751-A1 | Dihydropyridine alkanol amines, process for their preparation and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-09-17 | — | — | EP | disclosed |
| EP-0194752-A1 | Dihydropyridine alkanol amines, process for their preparation and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-09-17 | — | — | EP | disclosed |
| EP-0194046-A1 | Dihydropyridine alkanol amines, process for their preparation and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-09-10 | — | — | EP | disclosed |
| EP-0003664-A1 | Alkanolamine derivatives, process for their preparation and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-08-22 | — | — | EP | disclosed |