Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5387416 | 0.93 | DNM1 (0.45) | SPHK1DNM1OPRM1HTTTP53 | |
| SCHEMBL27578847 | 0.91 | DNM1 (0.48) | SPHK1DNM1OPRM1HTTTP53 | |
| SCHEMBL27795023 | 0.91 | DNM1 (0.48) | SPHK1DNM1OPRM1HTTTP53 | |
| SCHEMBL11172596 | 0.78 | CYP2D6 (0.42) | SPHK1ADRB2ADRB1ADRB3DNM1 | |
| SCHEMBL17663532 | 0.78 | TSHR (0.39) | SPHK1ADRB2ADRB1ADRB3DNM1 | |
| SCHEMBL9730288 | 0.76 | TSHR (0.37) | SPHK1ADRB2ADRB1ADRB3DNM1 | |
| SCHEMBL9729913 | 0.76 | TSHR (0.37) | SPHK1ADRB2ADRB1ADRB3DNM1 | |
| SCHEMBL873337 | 0.76 | TSHR (0.37) | SPHK1ADRB2ADRB1ADRB3DNM1 | |
| SCHEMBL10956724 | 0.76 | CYP3A4 (0.38) | SPHK1ADRB2ADRB1ADRB3DNM1 | |
| SCHEMBL9731348 | 0.76 | TSHR (0.37) | SPHK1ADRB2ADRB1ADRB3DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063075-A | Amide ether derivatives as low calorie fat mimetics | NABISCO BRANDS, INC. (US) | 1991-11-05 | — | — | US | disclosed |