Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL419730 | 0.85 | EPHX2 (0.61) | EPHX2EPHX1L3MBTL1LIPE | |
| SCHEMBL419732 | 0.85 | EPHX2 (0.61) | EPHX2EPHX1L3MBTL1LIPE | |
| SCHEMBL419731 | 0.85 | EPHX2 (0.61) | EPHX2EPHX1L3MBTL1LIPE | |
| SCHEMBL7895732 | 0.79 | EPHX2 (0.51) | EPHX2EPHX1L3MBTL1DPP4DPP7 | |
| SCHEMBL539326 | 0.79 | EPHX2 (0.42) | EPHX2EPHX1MMP9MMP1MMP13 | |
| SCHEMBL539061 | 0.76 | EPHX2 (0.46) | EPHX2EPHX1MMP9MMP1MMP13 | |
| SCHEMBL426160 | 0.75 | EPHX2 (0.52) | EPHX2EPHX1L3MBTL1DPP4LIPE | |
| SCHEMBL426158 | 0.75 | EPHX2 (0.52) | EPHX2EPHX1L3MBTL1DPP4LIPE | |
| SCHEMBL426159 | 0.75 | EPHX2 (0.52) | EPHX2EPHX1L3MBTL1DPP4LIPE | |
| SCHEMBL2171738 | 0.74 | EPHX2 (0.43) | EPHX2EPHX1MMP9MMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414332-A1 | ACRYLAMIDE COMPOUNDS AND THE USE THEREOF | Shionogi & Co., Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010114181-A1 | ACRYLAMIDE COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2010-10-07 | — | — | WO | disclosed |