Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 6/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1677139 | 0.83 | EPHX2 (0.57) | EPHX2LIPEMEN1KMT2AMMP13 | |
| SCHEMBL539326 | 0.76 | EPHX2 (0.42) | EPHX2LIPEMEN1KMT2AMMP13 | |
| SCHEMBL2173168 | 0.75 | EPHX2 (0.57) | EPHX2LIPEMEN1KMT2AMMP13 | |
| SCHEMBL539061 | 0.75 | EPHX2 (0.46) | EPHX2LIPEMEN1KMT2AMMP13 | |
| SCHEMBL538758 | 0.74 | EPHX2 (0.46) | EPHX2LIPEMMP13MMP1MMP9 | |
| SCHEMBL1676913 | 0.73 | EPHX2 (0.63) | EPHX2LIPEMEN1KMT2AMMP13 | |
| SCHEMBL3717658 | 0.72 | ALDH1A1 (0.56) | EPHX2LIPEMEN1KMT2AMMP13 | |
| SCHEMBL1676930 | 0.71 | EPHX2 (0.52) | EPHX2LIPEMEN1KMT2AMMP13 | |
| SCHEMBL1677075 | 0.71 | EPHX2 (0.56) | EPHX2LIPEMEN1KMT2AMMP13 | |
| SCHEMBL1677130 | 0.71 | EPHX2 (0.52) | EPHX2LIPEMEN1KMT2AMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346820-A1 | OXYCARBAMOYL COMPOUNDS AND THE USE THEREOF | Shionogi & Co., Ltd. (JP) | 2011-07-27 | — | — | EP | disclosed |
| WO-2009151152-A1 | OXYCARBAMOYL COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2009-12-17 | — | — | WO | disclosed |