SCHEMBL5387844

SCHEMBL5387844

CCCc1cc(N(C)C)ccc1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC16A3 O15427 1/20 0.43
ALDH1A1 P00352 4/20 0.40
KDM4E B2RXH2 3/20 0.40
PTPN1 P18031 1/20 0.39
PTPN11 Q06124 1/20 0.39
RXRA P19793 2/20 0.39
PPARA Q07869 2/20 0.39
MCL1 Q07820 1/20 0.39
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
POLB P06746 2/20 0.38
GAA P10253 1/20 0.38
MYC P01106 1/20 0.38
GABRP O00591 1/20 0.38
GABRD O14764 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRB1 P18505 1/20 0.38
GABRG2 P18507 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4914947 0.90 GABRP (0.49) SLC16A3ALDH1A1KDM4ERXRAPPARA
SCHEMBL480460 0.89 PPARA (0.49) ALDH1A1KDM4EPPARAMCL1POLB
SCHEMBL7601521 0.88 SLC16A3 (0.46) SLC16A3ALDH1A1KDM4EMEN1KMT2A
SCHEMBL41899 0.88 SLC16A3 (0.46) SLC16A3ALDH1A1KDM4EMEN1KMT2A
SCHEMBL6247855 0.88 PPARA (0.51) PPARAMCL1GABRPGABRDGABRA1
SCHEMBL38613 0.88 PPARA (0.51) PPARAMCL1GABRPGABRDGABRA1
SCHEMBL9517713 0.88 PPARA (0.51) PPARAMCL1GABRPGABRDGABRA1
SCHEMBL4889679 0.88 PPARA (0.51) PPARAMCL1GABRPGABRDGABRA1
SCHEMBL3305470 0.87 SLC16A3 (0.43) SLC16A3ALDH1A1KDM4EPPARAMYC
SCHEMBL2007047 0.87 PTPN1 (0.39) ALDH1A1KDM4EPTPN1PTPN11RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7189488-B2 Polyimide precursor, manufacturing method thereof, and resin composition using polyimide precursor KANEKA CORPORATION (JP) 2007-03-13 US disclosed
US-20030149142-A1 Polyimide precursor, manufacturing method thereof, and resin composition using polyimide precursor KANEKA CORPORATION 2003-08-07 US disclosed