SCHEMBL2007047

SCHEMBL2007047

CCCc1cc(N(O)O)ccc1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.39
PTPN11 Q06124 1/20 0.39
RXRA P19793 2/20 0.39
PPARA Q07869 2/20 0.39
MCL1 Q07820 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
GABRP O00591 2/20 0.38
GABRD O14764 2/20 0.38
GABRA1 P14867 2/20 0.38
GABRB1 P18505 2/20 0.38
GABRG2 P18507 2/20 0.38
GABRB3 P28472 2/20 0.38
GABRA5 P31644 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7877999 0.88 GABRP (0.42) RXRAPPARAMEN1KMT2ASMN1; SMN2
SCHEMBL5387844 0.87 SLC16A3 (0.43) PTPN1PTPN11RXRAPPARAMCL1
SCHEMBL5397794 0.85 MEN1 (0.54) PTPN1PTPN11RXRAMEN1KMT2A
SCHEMBL9150935 0.81 CA12 (0.45) MEN1KMT2AL3MBTL1KDM4EALDH1A1
SCHEMBL80902 0.79 RXRA (0.52) PTPN1PTPN11RXRAPPARAMCL1
SCHEMBL4914947 0.78 GABRP (0.49) RXRAPPARAMCL1SMN1; SMN2KDM4E
SCHEMBL9745 0.77 PTPN1 (0.54) PTPN1PTPN11PPARAMCL1SMN1; SMN2
SCHEMBL3840599 0.77 RXRA (0.51) PTPN1PTPN11RXRAPPARAMCL1
SCHEMBL2809370 0.77 CSNK2A1 (0.48) PTPN1PTPN11RXRAPPARAMCL1
SCHEMBL15344558 0.77 PPARA (0.53) PTPN1PTPN11RXRAPPARAMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1740152-B1 POLY(SILSESQUIOXANE) SPHERICAL PARTICLE CONTAINING ULTRAVIOLET LIGHT-ABSORBING GROUP AND MANUFACTURING METHOD THEREOF SAIMDANG COSMETICS CO LTD (KR) 2012-12-26 EP claimed
US-7964747-B2 Poly(silsesquioxane) spherical particle containing ultraviolet light-absorbing group and manufacturing method thereof Saimdang Cosmetics, Co., Ltd. (KR) 2011-06-21 US claimed
US-20070249854-A1 Poly(Silsesquioxane) Spherical Particle Containing Ultraviolet Light-Absorbing Group and Manufacturing Method Thereof SAIMDANG COSMETICS CO., LTD. (KR) 2007-10-25 US claimed
EP-1740152-A1 POLY(SILSESQUIOXANE) SPHERICAL PARTICLE CONTAINING ULTRAVIOLET LIGHT-ABSORBING GROUP AND MANUFACTURING METHOD THEREOF Saimdang Cosmetics Co., Ltd. (KR) 2007-01-10 EP claimed
WO-2005105028-A1 POLY(SILSESQUIOXANE) SPHERICAL PARTICLE CONTAINING ULTRAVIOLET LIGHT-ABSORBING GROUP AND MANUFACTURING METHOD THEREOF SAIMDANG COSMETICS CO., LTD. (KR) 2005-11-10 WO claimed
EP-1740152-B1 POLY(SILSESQUIOXANE) SPHERICAL PARTICLE CONTAINING ULTRAVIOLET LIGHT-ABSORBING GROUP AND MANUFACTURING METHOD THEREOF SAIMDANG COSMETICS CO LTD (KR) 2012-12-26 EP disclosed
US-7993630-B2 Protection of skin from UV and peroxide BIODERM RESEARCH (US) 2011-08-09 US disclosed
US-7964747-B2 Poly(silsesquioxane) spherical particle containing ultraviolet light-absorbing group and manufacturing method thereof Saimdang Cosmetics, Co., Ltd. (KR) 2011-06-21 US disclosed
US-20090269291-A1 Protection of Skin from UV and Peroxide BIODERM RESEARCH (US) 2009-10-29 US disclosed
US-7597879-B2 Sunscreen safety and efficacy enhancement BIODERM RESEARCH (US) 2009-10-06 US disclosed
US-20070249854-A1 Poly(Silsesquioxane) Spherical Particle Containing Ultraviolet Light-Absorbing Group and Manufacturing Method Thereof SAIMDANG COSMETICS CO., LTD. (KR) 2007-10-25 US disclosed
US-20070189992-A1 Sunscreen Safety and Efficacy Enhancement with Manganese Complexes via Urocanate Pathway BIODERM RESEARCH (US) 2007-08-16 US disclosed
EP-1740152-A1 POLY(SILSESQUIOXANE) SPHERICAL PARTICLE CONTAINING ULTRAVIOLET LIGHT-ABSORBING GROUP AND MANUFACTURING METHOD THEREOF Saimdang Cosmetics Co., Ltd. (KR) 2007-01-10 EP disclosed
WO-2005105028-A1 POLY(SILSESQUIOXANE) SPHERICAL PARTICLE CONTAINING ULTRAVIOLET LIGHT-ABSORBING GROUP AND MANUFACTURING METHOD THEREOF SAIMDANG COSMETICS CO., LTD. (KR) 2005-11-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070249854-A1 Poly(Silsesquioxane) Spherical Particle Containing Ultraviolet Light-Absorbing Group and Manufacturing Method Thereof STS, PARG, SBDS PTPN1 4393/4885PTPN11 4358/4885RXRA 1195/4885
US-20090269291-A1 Protection of Skin from UV and Peroxide SOD3, UROD, SOD1 PTPN1 3595/4885PTPN11 3722/4885RXRA 172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.